Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …

The transient receptor potential vanilloid-1 (TRPV1) is a non-specific cation channel known
for its sensitivity to pungent vanilloid compound (ie capsaicin) and noxious stimuli, including …

Heat exchange processes between the body and the environment are introduced. The
definition of the thermoneutral zone as the ambient temperature range within which body …

Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body
temperature (T b) in laboratory animals and humans: most cause hyperthermia; some …

Chronic pain treatment remains a sore challenge, and in our aging society, the number of
patients reporting inadequate pain relief continues to grow. Current treatment options all …

The capsaicin (vanilloid) receptor, TRPV1, is a heat-activated cation channel modulated by
inflammatory mediators and contributes to acute and chronic pain. TRPV1 channel is one of …

Transient receptor potential vanilloid 1 (TRPV1) channels are widely distributed in sensory
nerve endings, the central nervous system, and other tissues, functioning as ion channel …

Chronic pain is a common symptom experienced during cancer progression. Additionally,
some patients experience bone pain caused by cancer metastasis, which further …

A fundamental subdivision of nociceptive sensory neurons is named after their unique
sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin …

Pain in trigeminal areas is driven by nociceptive trigeminal afferents. Transduction
molecules, among them the nonspecific cation channels transient receptor potential …