Epigallocatechin 3-gallate: From green tea to cancer therapeutics

M Alam, S Ali, GM Ashraf, AL Bilgrami, DK Yadav… - Food chemistry, 2022 - Elsevier
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …

The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International journal of molecular sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

Prooxidant effects of epigallocatechin‐3‐gallate in health benefits and potential adverse effect

J Ouyang, K Zhu, Z Liu, J Huang - Oxidative Medicine and …, 2020 - Wiley Online Library
Epigallocatechin‐3‐gallate (EGCG) is the major polyphenolic compound present in green
tea and is generally regarded as an effective antioxidant. However, its chemical reactivity …

[HTML][HTML] Managing obesity through natural polyphenols: A review

M Singh, T Thrimawithana, R Shukla, B Adhikari - Future Foods, 2020 - Elsevier
Obesity is a pervasive global health problem needing urgent research and regulatory
attention. Although synthetic anti-obesity drugs are available, they come with considerable …

Therapeutic activity of green tea epigallocatechin-3-gallate on metabolic diseases and non-alcoholic fatty liver diseases: The current updates

A James, K Wang, Y Wang - Nutrients, 2023 - mdpi.com
Green tea polyphenols have numerous functions including antioxidation and modulation of
various cellular proteins and are thus beneficial against metabolic diseases including …

Effects of green tea polyphenol extract and epigallocatechin-3-O-gallate on diabetes mellitus and diabetic complications: Recent advances

C Wan, J Ouyang, M Li… - Critical reviews in food …, 2024 - Taylor & Francis
Diabetes mellitus is one of the major non-communicable diseases accounting for millions of
death annually and increasing economic burden. Hyperglycemic condition in diabetes …

Epigallocatechin gallate for management of heavy metal-induced oxidative stress: Mechanisms of action, efficacy, and concerns

I Zwolak - International Journal of Molecular Sciences, 2021 - mdpi.com
In this review, we highlight the effects of epigallocatechin gallate (EGCG) against toxicities
induced by heavy metals (HMs). This most active green tea polyphenol was demonstrated to …

Zein-polysaccharide nanoparticles as matrices for antioxidant compounds: A strategy for prevention of chronic degenerative diseases

JA Tapia-Hernández, F Rodríguez-Felix… - Food Research …, 2018 - Elsevier
Oxidative Stress (OS) produces the formation of free radicals and other reactive oxygen and
nitrogen species that are intimately involved in many diseases, especially Chronic …

Protective effects of epigallocatechin gallate (EGCG) on endometrial, breast, and ovarian cancers

YJ Huang, KL Wang, HY Chen, YF Chiang, SM Hsia - Biomolecules, 2020 - mdpi.com
Green tea and its major bioactive component,(−)-epigallocatechin gallate (EGCG), possess
diverse biological properties, particularly antiproliferation, antimetastasis, and apoptosis …