Cardiovascular diseases are the leading cause of global deaths, and many risk factors
contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic …

Activation of the immune system by ANG II contributes to the pathogenesis of hypertension,
and pharmacological suppression of lymphocyte responses can ameliorate hypertensive …

Emerging evidence has demonstrated that (pro) renin receptor (PRR)-mediated activation of
intrarenal renin-angiotensin system (RAS) plays an essential role in renal handling of Na+ …

Pharmacological suppression of cyclooxygenase (COX)-1 and-2-mediated prostanoid
biosynthesis by non steroidal anti-inflammatory drugs (NSAIDs) is used in the therapy of …

Objective To study the antioxidant properties of Capparis spinosa (C. spinosa) honey and
propolis and the effect of combined honey and propolis administration on urine volume and …

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used
therapeutic class in clinical medicine. These are sub-divided based on their selectivity for …

Salt (NaCl) is a prerequisite for life. Excessive intake of salt, however, is said to increase
disease risk, including hypertension, arteriosclerosis, heart failure, renal disease, stroke …

Prostanoids are prominent, yet complex, components in the maintenance of body water
homeostasis. Recent functional and molecular studies have revealed that the local lipid …

(Pro) renin receptor (PRR) is predominantly expressed in the distal nephron where it is
activated by angiotensin II (ANG II), resulting in increased renin activity in the renal medulla …

Fluid shear stress (FSS) is a critical regulator of cation transport in the collecting duct (CD).
High-dietary sodium (Na) consumption increases urine flow, Na excretion, and …