ATP and its ultimate degradation product adenosine are potent extracellular signalling
molecules that elicit a variety of pathophysiological functions in the kidney through the …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Physical exercise represents an effective preventive and therapeutic strategy beneficially
modifying the course of multiple diseases. The protective mechanisms of exercise are …

A lack of physical activity is linked to the development of many chronic diseases through a
chronic low-grade inflammation state. It is now well accepted that the immune system plays …

Immune cells are bioenergetically expensive during activation, which requires tightly
regulated control of metabolic pathways. Both low and high glycemic conditions can …

Molecules such as cytokines, energetic substrates, and hormones found in the immune cell
environment, especially lymphocytes and monocytes, are crucial for directing energy …

Many of the exercise-related health-promoting effects are attributed to beneficial
immunomodulation. The restoration of immune homeostasis is context-dependent, meaning …

Purinergic signaling modulates immune function and is involved in the
immunopathogenesis of several viral infections. This study aimed to investigate alterations …

Current Knowledge and New Challenges in Exercise Immunology Page 1 250 GERMAN
JOURNAL OF SPORTS MEDICINE 70 10/2019 Zusammenfassung Summary ACCEPTED …

This study investigated the peripheral frequency of monocytes, CD4+ T cell subsets and the
systemic levels of cytokines in lean and obese men with different levels of cardiorespiratory …