Oxidative stress is known to be an inseparable factor involved in the presentation of liver
disorders. Free radicals interfere with DNA, proteins, and lipids, which are crucial in liver …

Protein arginine methyltransferases (PRMTs) promote the methylation of numerous proteins
at their arginine residues. An increasing number of publications have suggested that …

One of the key mechanisms of alcoholic liver disease is oxidative stress. Both Curcumin and
Baicalin exert antioxidant effects, but the mechanism of their combined effects of ethanol …

Rationale: Over-nutrition will lead to overexpression of PRMT1 but protein hypomethylation
is observed in the liver of obese subjects. The dynamic alteration of the expression and …

Extracellular matrix (ECM) rigidity has important effects on cell behaviors and increases
sharply in liver fibrosis and cirrhosis. Hepatic blood flow is essential in maintaining …

Alcohol-related liver disease (ALD) is one of the most prevalent forms of liver disease in the
world. Acetaldehyde, an intermediate product of alcohol catabolism, is a cause of liver injury …

Background & Aims Alcohol-associated liver disease (ALD) comprises a spectrum of
disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. We aimed to study the …

The therapeutic effect of irradiation is thought to come from DNA damage that affects rapidly
proliferating cancer cells; however, resistant cells rapidly initiate mechanisms to repair such …

The epigenetic state of chromatin is altered by regulators which influence gene expression
in response to environmental stimuli. While several post-translational modifications …

Consuming alcohol affects almost all organs. Acetaldehyde, formed as the main product as
a result of alcohol metabolism, causes the production of free superoxide radicals when …