Radiation-induced lung injury (RILI)
L Giuranno, J Ient, D De Ruysscher, MA Vooijs - Frontiers in oncology, 2019 - frontiersin.org
Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …
Two decades of SPECT/CT–the coming of age of a technology: an updated review of literature evidence
O Israel, O Pellet, L Biassoni, D De Palma… - European journal of …, 2019 - Springer
Purpose Single-photon emission computed tomography (SPECT) combined with computed
tomography (CT) was introduced as a hybrid SPECT/CT imaging modality two decades ago …
tomography (CT) was introduced as a hybrid SPECT/CT imaging modality two decades ago …
Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues
SM Bentzen, LS Constine, JO Deasy, A Eisbruch… - International Journal of …, 2010 - Elsevier
Advances in dose–volume/outcome (or normal tissue complication probability, NTCP)
modeling since the seminal Emami paper from 1991 are reviewed. There has been some …
modeling since the seminal Emami paper from 1991 are reviewed. There has been some …
Radiation dose–volume effects in the lung
The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The
rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no …
rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no …
Non–small cell lung cancer
DS Ettinger, W Akerley, G Bepler, MG Blum… - Journal of the national …, 2010 - jnccn.org
Lung cancer is the leading cause of cancer-related death in the United States. An estimated
219,440 new cases (116,090 men; 103,350 women) of lung and bronchus cancer were …
219,440 new cases (116,090 men; 103,350 women) of lung and bronchus cancer were …
Radiation pneumonitis
TJ Bledsoe, SK Nath… - Clinics in chest medicine, 2017 - chestmed.theclinics.com
Although radiation therapy provides the backbone of primary and adjuvant therapy for
several thoracic malignancies, the lungs have long been known to be exquisitely sensitive to …
several thoracic malignancies, the lungs have long been known to be exquisitely sensitive to …
Effect of midtreatment PET/CT-adapted radiation therapy with concurrent chemotherapy in patients with locally advanced non–small-cell lung cancer: a phase 2 …
Importance Our previous studies demonstrated that tumors significantly decrease in size and
metabolic activity after delivery of 45 Gy of fractionated radiatiotherapy (RT), and that …
metabolic activity after delivery of 45 Gy of fractionated radiatiotherapy (RT), and that …
Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus
T Ritter, DJ Quint, S Senan, LE Gaspar… - International Journal of …, 2011 - Elsevier
PURPOSE: To review the dose limits and standardize the three-dimenional (3D)
radiographic definition for the organs at risk (OARs) for thoracic radiotherapy (RT), including …
radiographic definition for the organs at risk (OARs) for thoracic radiotherapy (RT), including …
The role of the mammalian target of rapamycin (mTOR) in pulmonary fibrosis
J Lawrence, R Nho - International journal of molecular sciences, 2018 - mdpi.com
The phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of
rapamycin (mTOR)-dependent pathway is one of the most integral pathways linked to cell …
rapamycin (mTOR)-dependent pathway is one of the most integral pathways linked to cell …
Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications
Purpose: Cancer treatment is one of the most challenging diseases in the present era.
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …