Mast cells and their progenitors in allergic asthma
E Méndez-Enríquez, J Hallgren - Frontiers in immunology, 2019 - frontiersin.org
Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …
The ingenious mast cell: Contemporary insights into mast cell behavior and function
Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …
KIT as a master regulator of the mast cell lineage
The discovery in 1987/1988 and 1990 of the cell surface receptor KIT and its ligand, stem
cell factor (SCF), was a critical achievement in efforts to understand the development and …
cell factor (SCF), was a critical achievement in efforts to understand the development and …
Human mast cells and basophils—How are they similar how are they different?
G Varricchi, U Raap, F Rivellese… - Immunological …, 2018 - Wiley Online Library
Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …
since they are the most prominent source of histamine as well as numerous additional …
Hematopoiesis and mast cell development
Hematopoietic stem cells (HSCs) are defined based on their capacity to replenish
themselves (self-renewal) and give rise to all mature hematopoietic cell types (multi-lineage …
themselves (self-renewal) and give rise to all mature hematopoietic cell types (multi-lineage …
Controlling mast cell activation and homeostasis: work influenced by Bill Paul that continues today
HL Caslin, KN Kiwanuka, TT Haque… - Frontiers in …, 2018 - frontiersin.org
Mast cells are tissue resident, innate immune cells with heterogenous phenotypes tuned by
cytokines and other microenvironmental stimuli. Playing a protective role in parasitic …
cytokines and other microenvironmental stimuli. Playing a protective role in parasitic …
Immunophenotypic dissection of normal hematopoiesis
A Orfao, S Matarraz, M Perez-Andres, J Almeida… - Journal of …, 2019 - Elsevier
Flow cytometry immunophenotyping is essential for diagnosis, classification and monitoring
of clonal hematopoietic diseases, particularly of hematological malignancies and primary …
of clonal hematopoietic diseases, particularly of hematological malignancies and primary …
Novel approaches to treating advanced systemic mastocytosis
JA Gilreath, L Tchertanov… - Clinical pharmacology …, 2019 - Taylor & Francis
Mastocytosis is a myeloproliferative neoplasm characterized by expansion of abnormal mast
cells (MCs) in various tissues, including skin, bone marrow, gastrointestinal tract, liver …
cells (MCs) in various tissues, including skin, bone marrow, gastrointestinal tract, liver …
IgE contributes to atherosclerosis and obesity by affecting macrophage polarization, macrophage protein network, and foam cell formation
X Zhang, J Li, S Luo, M Wang, Q Huang… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: By binding to its high-affinity receptor FcεR1, IgE activates mast cells,
macrophages, and other inflammatory and vascular cells. Recent studies support an …
macrophages, and other inflammatory and vascular cells. Recent studies support an …
Human lung mast cells: therapeutic implications in asthma
Mast cells are strategically located in different compartments of the lung in asthmatic
patients. These cells are widely recognized as central effectors and immunomodulators in …
patients. These cells are widely recognized as central effectors and immunomodulators in …