Intestinal epithelial glycosylation in homeostasis and gut microbiota interactions in IBD

MR Kudelka, SR Stowell, RD Cummings… - Nature reviews …, 2020 - nature.com
Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

[HTML][HTML] Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C

S Tanwar, F Rhodes, A Srivastava… - World journal of …, 2020 - ncbi.nlm.nih.gov
At present chronic liver disease (CLD), the third commonest cause of premature death in the
United Kingdom is detected late, when interventions are ineffective, resulting in …

Serum biomarkers for inflammatory bowel disease

P Chen, G Zhou, J Lin, L Li, Z Zeng, M Chen… - Frontiers in …, 2020 - frontiersin.org
Background: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative
colitis, is a chronic, inflammatory disorder of the gastrointestinal tract. As the novel …

Systematic review—pancreatic involvement in inflammatory bowel disease

S Massironi, I Fanetti, C Viganò, L Pirola… - Alimentary …, 2022 - Wiley Online Library
Background Inflammatory bowel disease (IBD) is a chronic inflammatory immune‐mediated
disorder of the gut with frequent extra‐intestinal complications. Pancreatic involvement in …

Recent advances in clinical practice: a systematic review of isolated colonic Crohn's disease: the third IBD?

S Subramanian, A Ekbom, JM Rhodes - Gut, 2017 - gut.bmj.com
The genetics of isolated colonic Crohn's disease place it approximately midway between
Crohn's disease with small intestinal involvement and UC, making a case for considering it …

[HTML][HTML] Pancreatic involvement in inflammatory bowel disease: a review

FS Fousekis, VI Theopistos, KH Katsanos… - Journal of clinical …, 2018 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a multisystemic disease, and pancreatic manifestations
of IBD are not uncommon. The incidence of several pancreatic diseases in Crohn's disease …

Systematic review: new serological markers (anti-glycan, anti-GP2, anti-GM-CSF Ab) in the prediction of IBD patient outcomes

J Bonneau, C Dumestre-Perard… - Autoimmunity …, 2015 - Elsevier
Traditionally, IBD diagnosis is based on clinical, radiological, endoscopic, and histological
criteria. Biomarkers are needed in cases of uncertain diagnosis, or to predict disease course …

PR3-ANCA and panel diagnostics in pediatric inflammatory bowel disease to distinguish ulcerative colitis from Crohn's disease

MP Horn, AM Peter, F Righini Grunder, AB Leichtle… - PLoS …, 2018 - journals.plos.org
Background Accurate classification of patients with inflammatory bowel disease into the
subtypes ulcerative colitis (UC) and Crohn's disease (CD) is still a challenge, but important …

Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: the glycoproteins CUZD1 and GP2

L Komorowski, B Teegen, C Probst… - Journal of Crohn's …, 2013 - academic.oup.com
Background: Autoantibodies against exocrine pancreas (PAb) have been reported to be
pathognomonic markers of Crohn's disease (CD). Recently, the glycoprotein GP2 has been …

[HTML][HTML] Human glycoprotein-2 expressed in Brunner glands–A putative autoimmune target and link between Crohn's and coeliac disease

D Roggenbuck, A Goihl, M Sowa, S Lopens… - Clinical …, 2023 - Elsevier
Abstract Glycoprotein 2 (GP2) is an autoantigen in Crohn's (CD) and coeliac disease (CeD).
We assessed GP2-isoform (GP2 1–4)-expression in intestinal biopsies of paediatric patients …