Genomes of complex organisms encode an abundance and diversity of long noncoding
RNAs (lncRNAs) that are expressed throughout the cell and fulfill a wide variety of regulatory …

Vanadium is an element ubiquitously present in our planet's crust and thus there are several
organisms that use vanadium for activity or function of proteins. Examples are the vanadium …

A pseudoknot forms in an RNA when nucleotides in a loop pair with a region outside the
helices that close the loop. Pseudoknots occur relatively rarely in RNA but are highly …

RNA dynamics play a fundamental role in many cellular functions. However, there is no
general framework to describe these complex processes, which typically consist of many …

Novel, profound and unexpected roles of long non-coding RNAs (lncRNAs) are emerging in
critical aspects of gene regulation. Thousands of lncRNAs have been recently discovered in …

Nuclear export of unspliced and singly spliced viral mRNA is a critical step in the HIV life
cycle. The structural basis by which the virus selects its own mRNA among more abundant …

Abstract Model evaluation is a necessary step for better prediction and design of 3D RNA
structures. For proteins, this has been widely studied and the knowledge-based statistical …

Although RNAs play many cellular functions, little is known about the dynamics and
thermodynamics of these molecules. In principle, all-atom molecular dynamics simulations …

Ribonuclease P (RNase P) is one of the first ribozymes discovered and it is found in all
phylogenetic groups. It is responsible for processing the 5′ end of pre-tRNAs as well as …

The T‐loop is a frequently occurring five‐nucleotide motif found in the structure of noncoding
RNAs where it is commonly assumed to play an important role in stabilizing the tertiary RNA …