Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Fruits and vegetables are important components of a healthy diet. They are rich sources of
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …

Background and Purpose The growing epidemic of obesity and metabolic diseases
necessitates the development of novel strategies to prevent and treat such diseases. Current …

Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …

Calcitonin gene-related peptide (CGRP) is a highly potent vasoactive peptide released from
sensory nerves, which is now proposed to have protective effects in several cardiovascular …

Transient receptor potential vanilloid subtype 1 (TRPV1), a member of the transient receptor
potential vanilloid (TRPV) channel family, is a nonselective cation channel that is widely …

The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

Background: The effects of capsaicin on obesity and glucose homeostasis are still
controversial and the mechanisms underlying these effects remain largely unknown. This …