Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy

J Goldney, JA Sargeant, MJ Davies - Diabetologia, 2023 - Springer
Glucagon-like peptide-1 receptor agonists (GLP-1RAs, incretin mimetics) and dipeptidyl
peptidase-4 inhibitors (DPP-4is, incretin enhancers) are glucose-lowering therapies with …

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

R Simo, C Hernandez - Progress in Retinal and eye Research, 2015 - Elsevier
Diabetic retinopathy remains as a leading cause of blindness in developed countries.
Current treatments target late stages of DR when vision has already been significantly …

[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy

S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Sustained release of stromal cell derived factor-1 from an antioxidant thermoresponsive hydrogel enhances dermal wound healing in diabetes

Y Zhu, R Hoshi, S Chen, J Yi, C Duan… - Journal of Controlled …, 2016 - Elsevier
Diabetic foot ulcers (DFUs) are a severe complication of diabetes mellitus. Altered cell
migration due to microcirculatory deficiencies as well as excessive and prolonged reactive …

[HTML][HTML] Therapeutic role of growth factors in treating diabetic wound

SY Zheng, XX Wan, PA Kambey, Y Luo… - World journal of …, 2023 - ncbi.nlm.nih.gov
Wounds in diabetic patients, especially diabetic foot ulcers, are more difficult to heal
compared with normal wounds and can easily deteriorate, leading to amputation. Common …

Specific role of impaired glucose metabolism and diabetes mellitus in endothelial progenitor cell characteristics and function

KH Yiu, HF Tse - Arteriosclerosis, thrombosis, and vascular biology, 2014 - Am Heart Assoc
The disease burden of diabetes mellitus (DM) and its associated cardiovascular
complications represent a growing and major global health problem. Recent studies suggest …

Autologous stem cell therapy: how aging and chronic diseases affect stem and progenitor cells

AY Efimenko, TN Kochegura, ZA Akopyan… - BioResearch open …, 2015 - liebertpub.com
During recent years different types of adult stem/progenitor cells have been successfully
applied for the treatment of many pathologies, including cardiovascular diseases. The …

Endothelial progenitor cells in diabetic retinopathy

N Lois, RV McCarter, C O'Neill, RJ Medina… - Frontiers in …, 2014 - frontiersin.org
Diabetic retinopathy (DR) is a leading cause of visual impairment worldwide. Patients with
DR may irreversibly lose sight as a result of the development of diabetic macular edema …

Endothelial progenitor cells biology in diabetes mellitus and peripheral arterial disease and their therapeutic potential

A Pyšná, R Bém, A Němcová, V Fejfarová… - Stem cell reviews and …, 2019 - Springer
Endothelial progenitors are a population of cells with the inherent capacity to differentiate
into mature endothelial cells and proangiogenic paracrine action. These characteristics …

Endothelial progenitor cells as biomarkers of diabetes-related cardiovascular complications

J Benítez-Camacho, A Ballesteros… - Stem Cell Research & …, 2023 - Springer
Diabetes mellitus (DM) constitutes a chronic metabolic disease characterized by elevated
levels of blood glucose which can also lead to the so-called diabetic vascular complications …