Cardiovascular effects of caffeic acid and its derivatives: a comprehensive review

H Silva, NMF Lopes - Frontiers in physiology, 2020 - frontiersin.org
Caffeic acid (CA) and its phenethyl ester (CAPE) are naturally occurring hydroxycinnamic
acids with an interesting array of biological activities; eg, antioxidant, anti-inflammatory …

Recent progresses in the pharmacological activities of caffeic acid phenethyl ester

L Lv, H Cui, Z Ma, X Liu, L Yang - Naunyn-Schmiedeberg's Archives of …, 2021 - Springer
The past decades have seen a growing interest in natural products. Caffeic acid phenethyl
ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple …

Effects and mechanisms of QiShenYiQi pills and major ingredients on myocardial microcirculatory disturbance, cardiac injury and fibrosis induced by ischemia …

JY Han, Q Li, CS Pan, K Sun, JY Fan - Pharmacological Research, 2019 - Elsevier
Coronary heart disease remains a major threaten for public health worldwide, and
pharmacological or mechanical coronary reperfusion are currently used for treatment of …

Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review

S Akyol, V Ugurcu, A Altuntas, R Hasgul… - The Scientific World …, 2014 - Wiley Online Library
Caffeic acid phenethyl ester (CAPE), an active component of propolis, has been attracting
the attention of different medical and pharmaceutical disciplines in recent years because of …

Stability of caffeic acid phenethyl ester and its fluorinated derivative in rat plasma

X Wang, PD Bowman, SM Kerwin… - Biomedical …, 2007 - Wiley Online Library
The stability of caffeic acid phenethyl ester (CAPE) and its fluorinated derivative (FCAPE) in
rat plasma and conditions preventing their degradation are reported. Reverse‐phase high …

The role of CAPE in PI3K/AKT/mTOR activation and oxidative stress on testis torsion

Y Dilber, S Inan, GA Ercan, A Sencan - Acta histochemica, 2016 - Elsevier
Ischemia reperfusion injury arises from testicular torsion resulting in a loss of
spermatogenesis and significant germ cell apoptosis. This study evaluates the …

[PDF][PDF] Pathophysiology of myocardial ischemia reperfusion injury: a review

H Parlakpinar, MH Orum, M Sagir - Medicine Science, 2013 - dergipark.org.tr
Cardiovascular events are one of the leading causes of death in the world. Thrombolysis,
percutaneous transluminal coronary angioplasty, and coronary bypass surgery are the …

[HTML][HTML] Evaluation of the effects of caffeic acid phenethyl ester on prostaglandin E2 and two key cytokines involved in bleomycin-induced pulmonary fibrosis

A Larki-Harchegani, AA Hemmati, A Arzi… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): Pulmonary fibrosis (PF) is the most common outcome of a collection of diverse
lung disorders known as interstitial lung diseases. It is proposed that alterations in the levels …

Structure–activity relationships in the cytoprotective effect of caffeic acid phenethyl ester (CAPE) and fluorinated derivatives: effects on heme oxygenase-1 induction …

X Wang, S Stavchansky, SM Kerwin… - European journal of …, 2010 - Elsevier
To determine the relationship between catechol ring modifications and the activity of caffeic
acid phenethyl ester (CAPE) as a cytoprotective agent, six catechol ring-fluorinated CAPE …

Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia …

O Ozhan, H Parlakpinar, A Acet - Fundamental & Clinical …, 2021 - Wiley Online Library
Myocardial ischemia may occur as a result of pathophysiological and therapeutical
applications such as atherosclerosis, thromboembolism, percutaneous transluminal …