Glioma is the most common primary cancer of the central nervous system, and around 50%
of patients present with the most aggressive form of the disease, glioblastoma. Conventional …

Summary The European Association for Neuro-Oncology guideline provides
recommendations for the clinical care of adult patients with astrocytic and oligodendroglial …

Importance Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for
glioblastoma remain poor, and new treatments are needed. Objective To investigate …

Importance Clinical outcomes for glioblastoma remain poor. Treatment with immune
checkpoint blockade has shown benefits in many cancer types. To our knowledge, data from …

Simple Summary Glioblastoma is the most common and aggressive malignant primary brain
cancer in adults. The prognosis remains poor following standard-of-care treatment with …

Glioblastomas (GBMs) are aggressive brain tumors characterized by extensive inter-and
intratumor heterogeneity. Patient-derived models, such as organoids and explants, have …

Glioblastoma is the most common and lethal primary malignant brain tumor in adults.
Patients die from recurrent tumors that have become resistant to therapy. New strategies are …

Antisense miRNA oligonucleotides against miR-21 (AMO-21) have a therapeutic potential
for treatment of glioblastoma. However, glioblastoma-targeted delivery through systemic …

A recent joint meeting was held on January 30, 2014, with the US Food and Drug
Administration (FDA), National Cancer Institute (NCI), clinical scientists, imaging experts …

Glioblastoma is the most aggressive and the most common primary malignant brain tumor in
adults. Risk factors for glioblastoma are widely elusive and the clinical course is generally …