[HTML][HTML] Bordetella pertussis pathogenesis: current and future challenges

JA Melvin, EV Scheller, JF Miller… - Nature Reviews …, 2014 - nature.com
Pertussis, also known as whooping cough, has recently re-emerged as a major public health
threat despite high levels of vaccination against the aetiological agent Bordetella pertussis …

Pertussis across the globe: recent epidemiologic trends from 2000 to 2013

T Tan, T Dalby, K Forsyth, SA Halperin… - The Pediatric …, 2015 - journals.lww.com
Pertussis has reemerged as a problem across the world. To better understand the nature of
the resurgence, we reviewed recent epidemiologic data and we report disease trends from …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Pertactin-Negative Bordetella pertussis Strains: Evidence for a Possible Selective Advantage

SW Martin, L Pawloski, M Williams… - Clinical Infectious …, 2015 - academic.oup.com
An analysis assessing for associations between pertactin production and both clinical
presentation and vaccine history found a significant association between vaccination and …

[HTML][HTML] Rapid increase in pertactin-deficient Bordetella pertussis isolates, Australia

C Lam, S Octavia, L Ricafort, V Sintchenko… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
Acellular vaccines against Bordetella pertussis were introduced in Australia in 1997. By
2000, these vaccines had replaced whole-cell vaccines. During 2008–2012, a large …

Why the evolution of vaccine resistance is less of a concern than the evolution of drug resistance

DA Kennedy, AF Read - Proceedings of the National …, 2018 - National Acad Sciences
Vaccines and antimicrobial drugs both impose strong selection for resistance. Yet only drug
resistance is a major challenge for 21st century medicine. Why is drug resistance ubiquitous …

Waning Tdap effectiveness in adolescents

NP Klein, J Bartlett, B Fireman, R Baxter - Pediatrics, 2016 - publications.aap.org
METHODS: We modeled pertussis risk in relation to Tdap vaccination status among
adolescents beginning on their 10th birthday. We estimated the hazard ratio (HR) for each …

[HTML][HTML] Pathogen evolution during vaccination campaigns

T Day, DA Kennedy, AF Read, S Gandon - PLoS biology, 2022 - journals.plos.org
Following the initiation of the unprecedented global vaccination campaign against Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the …

Estimating the effectiveness of tetanus-diphtheria-acellular pertussis vaccine (Tdap) for preventing pertussis: evidence of rapidly waning immunity and difference in …

R Koepke, JC Eickhoff, RA Ayele… - The Journal of …, 2014 - academic.oup.com
Background. We estimated the vaccine effectiveness (VE) of tetanus-diphtheria-acellular
pertussis vaccine (Tdap) for preventing pertussis among adolescents during a statewide …

[HTML][HTML] Pertactin-deficient Bordetella pertussis, vaccine-driven evolution, and reemergence of pertussis

L Ma, A Caulfield, KK Dewan… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and
rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular …