Background: High-dose ionizing radiation (IR)(> 0.5 Gy) is an established risk factor for
cognitive impairments, but this cannot be concluded for low-to-moderate IR exposure (< 0.5 …

An adverse outcome pathway (AOP) is a conceptual construct of causally and sequentially
linked events, which occur during exposure to stressors, with an adverse outcome relevant …

Background: During World War II (WWII), the Manhattan Engineering District established a
secret laboratory in the mountains of northern New Mexico. The mission was to design …

Purpose: Mallinckrodt Chemical Works (MCW) was the earliest uranium processing facility in
the United States, and in 1942 produced the uranium oxide used for the first sustained and …

Elevated levels of naturally occurring uranium in groundwater have been found in small
geographic areas throughout the world. Relevant research was reviewed pertaining to …

Purpose The objectives are to analyze mortality risks in the extended follow-up of the French
uranium miners' cohort and to examine their potential relation to occupational exposure to …

Objectives The study objectives were to extend the follow-up of the Ontario uranium miners
cohort, one of the largest cohorts of uranium miners with low cumulative exposures, to …

Purpose To examine exposure–response relationships between ionizing radiation and
several mortality outcomes in a subgroup of 4,054 men of the German uranium miner cohort …

Updated analyses of mortality data are presented on 46,970 workers employed 1948–1999
at Rocketdyne (Atomics International). Overall, 5,801 workers were involved in radiation …

Despite extensive efforts in studying radioactive aerosols, including the transmission of
radionuclides in different chemical matrices throughout the body, the internal organ-specific …