N-terminal acetylation (NTA) is one of the most widespread protein modifications, which
occurs on most eukaryotic proteins, but is significantly less common on bacterial and …

Actin is one of the most abundant and essential intracellular proteins that mediates nearly
every form of cellular movement and underlies such key processes as embryogenesis …

Actin isoforms organize into distinct networks that are essential for the normal function of
eukaryotic cells. Despite a high level of sequence and structure conservation, subtle …

The implications of the existence of different actins expressed in epithelial cells for network
mechanics and dynamics is investigated by microrheology and confocal imaging. γ-actin …

Actin is the most abundant protein in the cytoplasm of eukaryotic cells and interacts with
hundreds of proteins to perform essential functions, including cell motility and cytokinesis …

About 80% of human proteins are amino-terminally acetylated (Nt-acetylated) by one of
seven Nt-acetyltransferases (NATs). Actin, the most abundant protein in the cytoplasm, has …

Abstract Inverted formin 2 (INF2) is a member of the formin family of actin assembly factors.
Dominant missense mutations in INF2 are linked to two diseases: focal segmental …

Development is a complex process that occurs throughout the life cycle. F-actin, a major
component of the cytoskeleton, is essential for the morphogenesis of tissues and organs …

Visceral myopathy is a life-threatening disease characterized by muscle weakness in the
bowel, bladder, and uterus. Mutations in smooth muscle γ-actin (ACTG2) are the most …

The great diversity in actin network architectures and dynamics is exploited by cells to drive
fundamental biological processes, including cell migration, endocytosis, and cell division …