Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Single-cell multi-omics technologies have revolutionized cancer research by allowing us to
examine individual cells at a molecular level. Unlike traditional bulk omics approaches …

Diffuse large B-cell lymphoma (DLBCL) not otherwise specified is the most common
aggressive non-Hodgkin lymphoma and a biologically heterogeneous disease. Despite the …

Purpose: Tumor-infiltrating B lymphocytes (TIL-B) have demonstrated prognostic and
predictive significance in solid cancers. In this study, we aimed to distinguish TIL-Bs from …

The differentiation, survival, and effector function of tumor-specific CD8+ cytotoxic T cells lie
at the center of antitumor immunity. Due to the lack of proper costimulation and the abundant …

Burkitt lymphoma (BL) is the most frequent B-cell lymphoma in pediatric patients. While most
patients are cured, a fraction of them are resistant to therapy. To investigate BL …

Chimeric antigen receptor T (CAR-T) cells targeting multiple antigens (Ag), may reduce the
risk of immune escape following the loss of the target Ag and further increase the efficacy of …

Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

MicroRNAs (miRNAs) are a type of non-coding RNA whose dysregulation is frequently
associated with the onset and progression of human cancers. miR-142, an ultra-conserved …

Lymphoid neoplasms represent a heterogeneous group of disease entities and subtypes
with markedly different molecular and clinical features. Beyond genetic alterations, lymphoid …