Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …

Worldwide, infertility affects 8-12% of couples of reproductive age and has become a
common problem. There are many ways to treat infertility, including medication, intrauterine …

Finding an effective therapeutic approach is a primary goal for current and future research
for amyotrophic lateral sclerosis (ALS), a fatal neurological disease characterized by …

The testis is a unique environment where immune responses are suppressed to allow the
development of sperm that possess autoimmunogenic antigens. There are several …

Ethical issues are a significant barrier to the use of embryonic stem cells in patients due to
their origin: human embryos. To further the development of stem cells in a patient …

The ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc (OSKM),
known as “Yamanaka factors,” can reprogram or stimulate the production of induced …

Induced pluripotent stem cells derived from normal somatic cells could be utilized to study
tumorigenesis through overexpression of specific oncogenes, downregulation of tumor …

The process of direct cell reprogramming, also named transdifferentiation, permits for the
conversion of one mature cell type directly into another, without returning to a …

Tissue engineering (TE) pursues the ambitious goal to heal damaged tissues. One of the
most successful TE approaches relies on the use of scaffolds specifically designed and …