[HTML][HTML] Immunological approaches to HIV cure

AR Ward, TM Mota, RB Jones - Seminars in immunology, 2021 - Elsevier
Combination antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV)
infection has proven remarkably successful–for those who can access and afford it–yet HIV …

HIV control: Is getting there the same as staying there?

P Goulder, SG Deeks - PLoS pathogens, 2018 - journals.plos.org
In this brief review and perspective, we address the question of whether the immune
responses that bring about immune control of acute HIV infection are the same as, or distinct …

Richer gut microbiota with distinct metabolic profile in HIV infected Elite Controllers

J Vesterbacka, J Rivera, K Noyan, M Parera, U Neogi… - Scientific reports, 2017 - nature.com
Gut microbiota dysbiosis features progressive HIV infection and is a potential target for
intervention. Herein, we explored the microbiome of 16 elite controllers (EC), 32 …

Rate and predictors of progression in elite and viremic HIV-1 controllers

A Leon, I Perez, E Ruiz-Mateos, JM Benito, M Leal… - Aids, 2016 - journals.lww.com
Background: The proportion of HIV controllers developing virologic, immunological or
clinical progression and the baseline predictors of these outcomes have not been assessed …

Differences in intermittent and continuous fecal shedding patterns between natural and experimental Mycobacterium avium subspecies paratuberculosis infections …

RM Mitchell, Y Schukken, A Koets, M Weber… - Veterinary …, 2015 - Springer
The objective of this paper is to study shedding patterns of cows infected with
Mycobacterium avium subsp. paratuberculosis (MAP). While multiple single farm studies of …

Immunologic and virologic progression in HIV controllers: the role of viral “blips” and immune activation in the ANRS CO21 CODEX study

N Noel, N Lerolle, C Lécuroux, C Goujard, A Venet… - PloS one, 2015 - journals.plos.org
Some HIV controllers (HICs) experience CD4+ T cell count loss and/or lose their ability to
control HIV. In this study, we investigated the rate of immunologic and/or virologic …

Undisclosed HIV infection and antiretroviral therapy use in the Kenya AIDS indicator survey 2012: relevance to national targets for HIV diagnosis and treatment

AA Kim, I Mukui, PW Young, J Mirjahangir… - Aids, 2016 - journals.lww.com
Objectives: This analysis assessed the impact of undisclosed HIV infection and antiretroviral
therapy (ART) on national estimates of diagnosed HIV and ART coverage in Kenya …

Transcriptomics and targeted proteomics analysis to gain insights into the immune-control mechanisms of HIV-1 infected elite controllers

W Zhang, AT Ambikan, M Sperk, R van Domselaar… - …, 2018 - thelancet.com
A small subset of HIV-1 infected individuals, the" Elite Controllers"(EC), can control viral
replication and restrain progression to immunodeficiency without antiretroviral therapy …

Demographics and natural history of HIV-1-infected spontaneous controllers of viremia

OO Yang, WG Cumberland, R Escobar, D Liao… - Aids, 2017 - journals.lww.com
Objectives: HIV-1-infected persons spontaneously controlling viremia without treatment
(SCV) are rare. Sex and race effects on prevalence and outcome are poorly defined, and it is …

A subset of extreme human immunodeficiency virus (HIV) controllers is characterized by a small HIV blood reservoir and a weak T-cell activation level

E Canouï, C Lécuroux… - Open forum …, 2017 - academic.oup.com
Background Human immunodeficiency virus controllers (HICs) form a heterogeneous group
of patients with regard to formal definitions, immunologic characteristics, and changes over …