Peptide drug development has made great progress in the last decade thanks to new
production, modification, and analytic technologies. Peptides have been produced and …

Over the past two decades, genetic code expansion (GCE)-enabled methods for
incorporating noncanonical amino acids (ncAAs) into proteins have significantly advanced …

The persistence of CD4+ T cells carrying latent human immunodeficiency virus-1 (HIV-1)
proviruses is the main barrier to a cure. New therapeutics to enhance HIV-1-specific immune …

The question of whether the human brain is an anatomical site of persistent HIV-1 infection
during suppressive antiretroviral therapy (ART) is critical, but remains unanswered. The …

Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into
proteins of interest by repurposing the cellular translation machinery. The development of …

Conspectus Expansion of the genetic code allows unnatural amino acids (Uaas) to be site-
specifically incorporated into proteins in live biological systems, thus enabling novel …

Unnatural amino acids (UAAs) have gained significant attention in protein engineering and
drug development owing to their ability to introduce new chemical functionalities to proteins …

In nature, a limited, conservative set of amino acids are utilized to synthesize proteins.
Genetic code expansion technique reassigns codons and incorporates noncanonical amino …

Protein tyrosine O-sulfation (PTS) plays a crucial role in extracellular biomolecular
interactions that dictate various cellular processes. It also involves in the development of …

Synthetic biology tools for regulating gene expression have many useful biotechnology and
therapeutic applications. Most tools developed for this purpose control gene expression at …