Three decades of ultrasound contrast agents: a review of the past, present and future improvements

P Frinking, T Segers, Y Luan, F Tranquart - Ultrasound in medicine & …, 2020 - Elsevier
Initial reports from the 1960s describing the observations of ultrasound contrast
enhancement by tiny gaseous bubbles during echocardiographic examinations prompted …

[HTML][HTML] Ultrasound contrast agent modeling: a review

M Versluis, E Stride, G Lajoinie, B Dollet… - Ultrasound in medicine & …, 2020 - Elsevier
Ultrasound is extensively used in medical imaging, being safe and inexpensive and
operating in real time. Its scope of applications has been widely broadened by the use of …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Microbubble agents: New directions

E Stride, T Segers, G Lajoinie, S Cherkaoui… - Ultrasound in medicine …, 2020 - Elsevier
Microbubble ultrasound contrast agents have now been in use for several decades and their
safety and efficacy in a wide range of diagnostic applications have been well established …

Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations

AJ Sojahrood, Q Li, H Haghi, R Karshafian… - Ultrasonics …, 2023 - Elsevier
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …

Effect of surfactants on jet break-up in drop-on-demand inkjet printing

E Antonopoulou, OG Harlen, M Rump, T Segers… - Physics of …, 2021 - pubs.aip.org
Jet formation and break-up in inkjet printing has been studied and understood mainly for
pure liquids. Questions remain as to the role of surfactants on the inkjet printing process at …

Buckling of lipidic ultrasound contrast agents under quasi-static load

G Chabouh, B van Elburg… - … of the Royal …, 2023 - royalsocietypublishing.org
Collapse of lipidic ultrasound contrast agents under high-frequency compressive load has
been historically interpreted by the vanishing of surface tension. By contrast, buckling of …

Lipid/PLGA hybrid microbubbles as a versatile platform for noninvasive image-guided targeted drug delivery

Y Chen, Y Liang, P Jiang, F Li, B Yu… - ACS applied materials & …, 2019 - ACS Publications
Microbubbles (MBs) have recently emerged as promising theranostic carriers for ultrasound
contrast imaging and drug delivery. However, conventional lipid-based MBs have a poor …

Monodisperse versus polydisperse ultrasound contrast agents: In vivo sensitivity and safety in rat and pig

A Helbert, E Gaud, T Segers, C Botteron… - Ultrasound in Medicine …, 2020 - Elsevier
Recent advances in the field of monodisperse microbubble synthesis by flow focusing allow
for the production of foam-free, highly concentrated and monodisperse lipid-coated …