Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Engineered antibody fragments and the rise of single domains

P Holliger, PJ Hudson - Nature biotechnology, 2005 - nature.com
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …

Correlates of protection for booster doses of the SARS-CoV-2 vaccine BNT162b2

T Hertz, S Levy, D Ostrovsky, H Oppenheimer… - Nature …, 2023 - nature.com
Vaccination, especially with multiple doses, provides substantial population-level protection
against COVID-19, but emerging variants of concern (VOC) and waning immunity represent …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

A critical comparison of protein microarray fabrication technologies

V Romanov, SN Davidoff, AR Miles, DW Grainger… - Analyst, 2014 - pubs.rsc.org
Of the diverse analytical tools used in proteomics, protein microarrays possess the greatest
potential for providing fundamental information on protein, ligand, analyte, receptor, and …

Protein and peptide arrays: recent trends and new directions

M Cretich, F Damin, G Pirri, M Chiari - Biomolecular engineering, 2006 - Elsevier
Microarrays of proteins and peptides make it possible the screening of thousands of binding
events in a parallel and high throughput fashion; therefore they are emerging as a powerful …

Mass spectrometry–based functional proteomics: from molecular machines to protein networks

T Köcher, G Superti-Furga - Nature methods, 2007 - nature.com
The study of protein-protein interactions by mass spectrometry is an increasingly important
part of post-genomics strategies to understand protein function. A variety of mass …

Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples

L Belov, KJ Matic, S Hallal, OG Best… - Journal of …, 2016 - Taylor & Francis
Extracellular vesicles (EV) are membranous particles (30–1,000 nm in diameter) secreted by
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes …

Protein microarrays for diagnostic assays

M Hartmann, J Roeraade, D Stoll, MF Templin… - Analytical and …, 2009 - Springer
Protein microarray technology has enormous potential for in vitro diagnostics (IVD).
Miniaturized parallelized immunoassays are perfectly suited to generating a maximum of …

Applications of antibody array platforms

BB Haab - Current opinion in biotechnology, 2006 - Elsevier
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample
volumes. The earliest and most widely used application of antibody arrays has been to …