Biological responses to physicochemical properties of biomaterial surface
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …
Engineered antibody fragments and the rise of single domains
P Holliger, PJ Hudson - Nature biotechnology, 2005 - nature.com
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …
Correlates of protection for booster doses of the SARS-CoV-2 vaccine BNT162b2
T Hertz, S Levy, D Ostrovsky, H Oppenheimer… - Nature …, 2023 - nature.com
Vaccination, especially with multiple doses, provides substantial population-level protection
against COVID-19, but emerging variants of concern (VOC) and waning immunity represent …
against COVID-19, but emerging variants of concern (VOC) and waning immunity represent …
Human body fluid proteome analysis
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
A critical comparison of protein microarray fabrication technologies
Of the diverse analytical tools used in proteomics, protein microarrays possess the greatest
potential for providing fundamental information on protein, ligand, analyte, receptor, and …
potential for providing fundamental information on protein, ligand, analyte, receptor, and …
Protein and peptide arrays: recent trends and new directions
Microarrays of proteins and peptides make it possible the screening of thousands of binding
events in a parallel and high throughput fashion; therefore they are emerging as a powerful …
events in a parallel and high throughput fashion; therefore they are emerging as a powerful …
Mass spectrometry–based functional proteomics: from molecular machines to protein networks
T Köcher, G Superti-Furga - Nature methods, 2007 - nature.com
The study of protein-protein interactions by mass spectrometry is an increasingly important
part of post-genomics strategies to understand protein function. A variety of mass …
part of post-genomics strategies to understand protein function. A variety of mass …
Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples
L Belov, KJ Matic, S Hallal, OG Best… - Journal of …, 2016 - Taylor & Francis
Extracellular vesicles (EV) are membranous particles (30–1,000 nm in diameter) secreted by
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes …
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes …
Protein microarrays for diagnostic assays
M Hartmann, J Roeraade, D Stoll, MF Templin… - Analytical and …, 2009 - Springer
Protein microarray technology has enormous potential for in vitro diagnostics (IVD).
Miniaturized parallelized immunoassays are perfectly suited to generating a maximum of …
Miniaturized parallelized immunoassays are perfectly suited to generating a maximum of …
Applications of antibody array platforms
BB Haab - Current opinion in biotechnology, 2006 - Elsevier
Antibody arrays are valuable for the parallel analysis of multiple proteins in small sample
volumes. The earliest and most widely used application of antibody arrays has been to …
volumes. The earliest and most widely used application of antibody arrays has been to …