Every year almost 500,000 new patients are diagnosed with hepatocellular carcinoma
(HCC), a primary malignancy of the liver that is associated with a poor prognosis. Numerous …

Cancer is the first cause of death in developed countries and the second in developing
countries. Concerning the most frequent worldwide-diagnosed cancer, primary liver cancer …

Bile acids (BAs) are crucial for the diagnosis, follow-up, and prognostics of liver and
intestinal disorders and other diseases affecting BA metabolism. A rapid, simple, and …

Liver fibrosis is a progression of chronic liver disease with lacks effective therapies at
present. Schisandrin B (Sch B), a bioactive compound extracted from the traditional Chinese …

Hepatocellular carcinoma (HCC) is the subtype of liver cancer with the highest incidence,
which is a heterogeneous malignancy with increasing incidence rate and high mortality. For …

The protective and therapeutic effects of fucoidan extract from Laminaria species against
liver damage induced by CCl4 in rats was investigated by monitoring the serum level and …

We have previously shown that high-fat cholesterol diet (HFCD)–induced fatty liver and
carbon tetrachloride (CCl4)–induced hepatic fibrosis are reduced in mice deficient in group …

Liver injuries induced by carbon tetrachloride (CCL4) or thioacetamide (TAA) are dependent
on cytochrome P450 2E1 (CYP2E1). CYP2A5 can be induced by TAA but not by CCL4. In …

The current study investigated hepatoprotective and antioxidant effects of Aegle marmelos
leaves extract. The major constituent present in the extract ie rutin was quantified by using …

Period 2 (Per2) is a key component of the core clock oscillator and is involved in regulating a
number of different biological processes and pathways. Here we report that Per2 plays a …