Mitochondria are highly dynamic organelles undergoing cycles of fusion and fission to
modulate their morphology, distribution, and function, which are referred as 'mitochondrial …

Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Metastatic breast cancer cells disseminate to organs with a soft microenvironment. Whether
and how the mechanical properties of the local tissue influence their response to treatment …

The diagnosis and management of pulmonary arterial hypertension (PAH) includes several
advances, such as a broader recognition of extrapulmonary vascular organ system …

Maintenance of mitochondrial function and integrity is critical for normal cell survival,
particularly in non-dividing cells with a high-energy demand such as cardiomyocytes. Well …

The endoplasmic reticulum (ER) and mitochondria are physically connected to form
dedicated structural domains known as mitochondria-associated ER membranes (MAMs) …

Rationale: Right ventricular (RV) fibrosis in pulmonary arterial hypertension contributes to
RV failure. While RV fibrosis reflects changes in the function of resident RV fibroblasts …

Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …

The age-related vasculature alteration is the prominent risk factor for vascular diseases
(VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular calcification (VC) and …

Mitochondrial metabolism plays a pivotal role in various cellular processes and fibrosis.
However, the mechanism underlying mitochondrial metabolic function and liver fibrosis …