Cell refractive index for cell biology and disease diagnosis: past, present and future

PY Liu, LK Chin, W Ser, HF Chen, CM Hsieh, CH Lee… - Lab on a Chip, 2016 - pubs.rsc.org
Cell refractive index is a key biophysical parameter, which has been extensively studied. It is
correlated with other cell biophysical properties including mechanical, electrical and optical …

Quantitative phase imaging in biomedicine

YK Park, C Depeursinge, G Popescu - Nature photonics, 2018 - nature.com
Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …

Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

KR Lee, K Kim, J Jung, JH Heo, S Cho, S Lee… - Sensors, 2013 - mdpi.com
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …

Diffraction phase microscopy: principles and applications in materials and life sciences

B Bhaduri, C Edwards, H Pham, R Zhou… - Advances in Optics …, 2014 - opg.optica.org
The main obstacle in retrieving quantitative phase with high sensitivity is posed by the phase
noise due to mechanical vibrations and air fluctuations that typically affect any …

Biosensor application of one-dimensional photonic crystal for malaria diagnosis

Ankita, B Suthar, A Bhargava - Plasmonics, 2021 - Springer
A simple one-dimensional photonic crystal with a defect layer is presented as a biosensor
for malaria diagnosis. Here, the defect layer is taken as blood sample of the patient where a …

Live-cell mass profiling: an emerging approach in quantitative biophysics

TA Zangle, MA Teitell - Nature methods, 2014 - nature.com
Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …

High-resolution three-dimensional imaging of red blood cells parasitized by Plasmodium falciparum and in situ hemozoin crystals using optical diffraction …

K Kim, HO Yoon, M Diez-Silva, M Dao… - … of biomedical optics, 2014 - spiedigitallibrary.org
We present high-resolution optical tomographic images of human red blood cells (RBC)
parasitized by malaria-inducing Plasmodium falciparum (Pf)-RBCs. Three-dimensional (3-D) …

Quantitative phase imaging trends in biomedical applications

T Cacace, V Bianco, P Ferraro - Optics and Lasers in Engineering, 2020 - Elsevier
In the last decades, the understanding of the complex biological mechanisms that regulate
the life and growth of single cells and their reciprocal interaction has steadily increased. In …

Deep learning-based cell identification and disease diagnosis using spatio-temporal cellular dynamics in compact digital holographic microscopy

T O'Connor, A Anand, B Andemariam… - Biomedical Optics …, 2020 - opg.optica.org
We demonstrate a successful deep learning strategy for cell identification and disease
diagnosis using spatio-temporal cell information recorded by a digital holographic …

Quantitative phase imaging for medical diagnosis

H Majeed, S Sridharan, M Mir, L Ma, E Min… - Journal of …, 2017 - Wiley Online Library
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …