The medial prefrontal cortex-hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical …

OY Chao, MA de Souza Silva, YM Yang… - … & Biobehavioral Reviews, 2020 - Elsevier
Rats and mice have been demonstrated to show episodic-like memory, a prototype of
episodic memory, as defined by an integrated memory of the experience of an object or …

The longevity of hippocampus‐dependent memory is orchestrated by the locus coeruleus‐noradrenergic system

N Hansen - Neural plasticity, 2017 - Wiley Online Library
The locus coeruleus is connected to the dorsal hippocampus via strong fiber projections. It
becomes activated after arousal and novelty, whereupon noradrenaline is released in the …

Medial prefrontal cortex role in recognition memory in rodents

JF Morici, P Bekinschtein, NV Weisstaub - Behavioural Brain Research, 2015 - Elsevier
The study of the neurobiology of recognition memory, defined by the integration of the
different components of experiences that support recollection of past experiences have been …

Activation of the lateral habenula‐ventral tegmental area neural circuit contributes to postoperative cognitive dysfunction in mice

J Xin, W Shan, J Li, H Yu, Z Zuo - Advanced Science, 2022 - Wiley Online Library
Postoperative cognitive dysfunction (POCD) is common and is associated with poor
outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that …

Locus coeruleus in memory formation and Alzheimer's disease

T James, B Kula, S Choi, SS Khan… - European Journal of …, 2021 - Wiley Online Library
Catecholamine neurons of the locus coeruleus (LC) in the dorsal pontine tegmentum
innervate the entire neuroaxis, with signaling actions implicated in the regulation of …

Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice

D De Bundel, G Gangarossa, A Biever… - Frontiers in behavioral …, 2013 - frontiersin.org
The circadian clock comprises a set of genes involved in cell-autonomous transcriptional
feedback loops that orchestrate the expression of a range of downstream genes, driving …

The importance of ventral hippocampal dopamine and norepinephrine in recognition memory

J Titulaer, C Björkholm, K Feltmann… - Frontiers in Behavioral …, 2021 - frontiersin.org
Dopaminergic neurons originating from the ventral tegmental area (VTA) and the locus
coeruleus are innervating the ventral hippocampus and are thought to play an essential role …

Synaptic modification by L-theanine, a natural constituent in green tea, rescues the impairment of hippocampal long-term potentiation and memory in AD mice

G Zhu, S Yang, Z Xie, X Wan - Neuropharmacology, 2018 - Elsevier
Synaptic refinement improves synaptic efficiency, which provides a possibility to improve
memory in Alzheimer's disease (AD). In the current study, we aimed to investigate the role of …

Consolidation of object recognition memory requires simultaneous activation of dopamine D1/D5 receptors in the amygdala and medial prefrontal cortex but not in the …

JI Rossato, A Radiske, CA Kohler, C Gonzalez… - Neurobiology of learning …, 2013 - Elsevier
The mesocorticolimbic dopaminergic system includes the ventral tegmental area (VTA) and
its projections to the amygdala (AMY), the hippocampus (HIP) and the medial prefrontal …

[HTML][HTML] Abnormal synaptic plasticity and impaired cognition in schizophrenia

XL Wu, QJ Yan, F Zhu - World journal of psychiatry, 2022 - ncbi.nlm.nih.gov
Schizophrenia (SCZ) is a severe mental illness that affects several brain domains with
relation to cognition and behaviour. SCZ symptoms are typically classified into three …