Neurovascular communication during CNS development

I Paredes, P Himmels, CR de Almodovar - Developmental cell, 2018 - cell.com
A precise communication between the nervous and the vascular systems is crucial for
proper formation and function of the central nervous system (CNS). Interestingly, this …

Generation of vascularized brain organoids to study neurovascular interactions

XY Sun, XC Ju, Y Li, PM Zeng, J Wu, YY Zhou… - elife, 2022 - elifesciences.org
Brain organoids have been used to recapitulate the processes of brain development and
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …

[HTML][HTML] Neurovascular crosstalk coordinates the central nervous system development

B Peguera, M Segarra, A Acker-Palmer - Current opinion in neurobiology, 2021 - Elsevier
Purpose of the review: The synchronic development of vascular and nervous systems is
orchestrated by common molecules that regulate the communication between both systems …

Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration

MRM Harrison, X Feng, G Mo, A Aguayo, J Villafuerte… - Elife, 2019 - elifesciences.org
The cardiac lymphatic vascular system and its potentially critical functions in heart patients
have been largely underappreciated, in part due to a lack of experimentally accessible …

Toward the next generation of vascularized human neural organoids

M Li, L Gao, L Zhao, T Zou, H Xu - Medicinal research reviews, 2023 - Wiley Online Library
Thanks to progress in the development of three‐dimensional (3D) culture technologies,
human central nervous system (CNS) development and diseases have been gradually …

Pituicyte cues regulate the development of permeable neuro-vascular interfaces

S Anbalagan, L Gordon, J Blechman, RL Matsuoka… - Developmental Cell, 2018 - cell.com
The hypothalamo-neurohypophyseal system (HNS) regulates homeostasis through the
passage of neurohormones and blood-borne proteins via permeable blood capillaries that …

Building bridges, not walls: spinal cord regeneration in zebrafish

V Cigliola, CJ Becker, KD Poss - Disease models & …, 2020 - journals.biologists.com
Spinal cord injury is a devastating condition in which massive cell death and disruption of
neural circuitry lead to long-term chronic functional impairment and paralysis. In mammals …

Endothelial cell-type-specific molecular requirements for angiogenesis drive fenestrated vessel development in the brain

S Parab, RE Quick, RL Matsuoka - Elife, 2021 - elifesciences.org
Vascular endothelial cells (vECs) in the brain exhibit structural and functional heterogeneity.
Fenestrated, permeable brain vasculature mediates neuroendocrine function, body-fluid …

In utero exposure to maternal anti–aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring

S Mader, L Brimberg, A Vo, JJ Strohl… - Science translational …, 2022 - science.org
The fetal brain is constantly exposed to maternal IgG before the formation of an effective
blood-brain barrier (BBB). Here, we studied the consequences of fetal brain exposure to an …

Cross-talk between blood vessels and neural progenitors in the developing brain

M Tata, C Ruhrberg - Neuronal Signaling, 2018 - portlandpress.com
The formation of the central nervous system (CNS) involves multiple cellular and molecular
interactions between neural progenitor cells (NPCs) and blood vessels to establish …