Environmental, mechanistic and evolutionary landscape of antibiotic persistence
C Bollen, E Louwagie, N Verstraeten, J Michiels… - EMBO …, 2023 - embopress.org
Recalcitrant infections pose a serious challenge by prolonging antibiotic therapies and
contributing to the spread of antibiotic resistance, thereby threatening the successful …
contributing to the spread of antibiotic resistance, thereby threatening the successful …
Advances in linking single-cell bacterial stress response to population-level survival
RN Alnahhas, MJ Dunlop - Current opinion in biotechnology, 2023 - Elsevier
Highlights•Heterogeneity in phenotype and growth rate of single cells affect stress
survival.•Single-cell stress responses in biofilms and interspecies interactions can alter …
survival.•Single-cell stress responses in biofilms and interspecies interactions can alter …
(P) ppGpp synthetase Rsh participates in rifampicin tolerance of persister cells in Brucella abortus in vitro
X Liu, P Wang, Y Shi, Y Cui, S Li, GW Dong, J Li… - Microbial …, 2023 - Elsevier
Brucella abortus is facultative intracellular pathogen that causes chronic persistent infections
and results in abortion and infertility in food animals. Recurrent infections can be one of the …
and results in abortion and infertility in food animals. Recurrent infections can be one of the …
Roseateles albus sp. nov., Roseateles koreensis sp. nov. and Janthinobacterium fluminis sp. nov., isolated from freshwater at Jucheon River, and emended …
S Park, I Kim, G Chhetri, Y So… - … of Systematic and …, 2023 - microbiologyresearch.org
Three Gram-stain-negative, facultatively anaerobic, rod-shaped, catalase-positive, oxidase-
negative bacterial strains were designated as hw1T, hw8T and hw3T. Strains hw1T, hw8T …
negative bacterial strains were designated as hw1T, hw8T and hw3T. Strains hw1T, hw8T …
A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine
Many AAA+ (ATPases associated with diverse cellular activities) proteins function as protein
or DNA remodelers by threading the substrate through the central pore of their hexameric …
or DNA remodelers by threading the substrate through the central pore of their hexameric …
Fluoroquinolone and beta-lactam antimicrobials induce different transcriptome profiles in Salmonella enterica persister cells
Here, we investigate the transcriptome profiles of two S. Enteritidis and one S.
Schwarzengrund isolates that present different persister levels when exposed to …
Schwarzengrund isolates that present different persister levels when exposed to …
Cellular self-digestion and persistence in Bacteria
Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells
that enables survival under stressful conditions by recycling essential energy molecules …
that enables survival under stressful conditions by recycling essential energy molecules …
Exploring the links between SOS response, mutagenesis, and resistance during the recovery period
Although the mechanistic connections between SOS-induced mutagenesis and antibiotic
resistance are well established, our current understanding of the impact of SOS response …
resistance are well established, our current understanding of the impact of SOS response …
[HTML][HTML] Characterization of Clostridioides difficile Persister Cells and Their Role in Antibiotic Tolerance
O Inostroza, JA Fuentes, P Yáñez, G Espinoza, O Fica… - Microorganisms, 2024 - mdpi.com
Clostridioides difficile is a Gram-positive pathogen known for its toxin production and spore
formation. It is primarily responsible for most cases of antibiotic-associated diarrhea …
formation. It is primarily responsible for most cases of antibiotic-associated diarrhea …
Resuscitation dynamics reveal persister partitioning after antibiotic treatment
X Fang, KR Allison - Molecular systems biology, 2023 - embopress.org
Bacteria can survive antibiotics by forming dormant, drug‐tolerant persisters. Persisters can
resuscitate from dormancy after treatment and prolong infections. Resuscitation is thought to …
resuscitate from dormancy after treatment and prolong infections. Resuscitation is thought to …