The molecular principles of gene regulation by Polycomb repressive complexes
NP Blackledge, RJ Klose - Nature reviews Molecular cell biology, 2021 - nature.com
Precise control of gene expression is fundamental to cell function and development.
Although ultimately gene expression relies on DNA-binding transcription factors to guide the …
Although ultimately gene expression relies on DNA-binding transcription factors to guide the …
[HTML][HTML] Genome regulation by polycomb and trithorax: 70 years and counting
B Schuettengruber, HM Bourbon, L Di Croce, G Cavalli - Cell, 2017 - cell.com
Polycomb (PcG) and Trithorax (TrxG) group proteins are evolutionarily conserved chromatin-
modifying factors originally identified as part of an epigenetic cellular memory system that …
modifying factors originally identified as part of an epigenetic cellular memory system that …
Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression
Plants use seasonal temperature cues to time the transition to reproduction. In Arabidopsis
thaliana, winter cold epigenetically silences the floral repressor locus FLOWERING LOCUS …
thaliana, winter cold epigenetically silences the floral repressor locus FLOWERING LOCUS …
Glucose-driven TOR–FIE–PRC2 signalling controls plant development
Nutrients and energy have emerged as central modulators of developmental programmes in
plants and animals,–. The evolutionarily conserved target of rapamycin (TOR) kinase is a …
plants and animals,–. The evolutionarily conserved target of rapamycin (TOR) kinase is a …
Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics
Plants grow in dynamic environments where they can be exposed to a multitude of stressful
factors, all of which affect their development, yield, and, ultimately, reproductive success …
factors, all of which affect their development, yield, and, ultimately, reproductive success …
The genetic basis of flowering responses to seasonal cues
F Andrés, G Coupland - Nature Reviews Genetics, 2012 - nature.com
Plants respond to the changing seasons to initiate developmental programmes precisely at
particular times of year. Flowering is the best characterized of these seasonal responses …
particular times of year. Flowering is the best characterized of these seasonal responses …
Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization
Long noncoding RNAs (lncRNAs) have been proposed to play important roles in gene
regulation. However, their importance in epigenetic silencing and how specificity is …
regulation. However, their importance in epigenetic silencing and how specificity is …
Vernalization-triggered intragenic chromatin loop formation by long noncoding RNAs
DH Kim, S Sung - Developmental cell, 2017 - cell.com
Long noncoding RNAs (lncRNAs) affect gene regulation through structural and regulatory
interactions with associated proteins. The Polycomb complex often binds to lncRNAs in …
interactions with associated proteins. The Polycomb complex often binds to lncRNAs in …
The FLC Locus: A Platform for Discoveries in Epigenetics and Adaptation
C Whittaker, C Dean - Annual review of cell and developmental …, 2017 - annualreviews.org
Our understanding of the detailed molecular mechanisms underpinning adaptation is still
poor. One example for which mechanistic understanding of regulation has converged with …
poor. One example for which mechanistic understanding of regulation has converged with …