The molecular principles of gene regulation by Polycomb repressive complexes

NP Blackledge, RJ Klose - Nature reviews Molecular cell biology, 2021 - nature.com
Precise control of gene expression is fundamental to cell function and development.
Although ultimately gene expression relies on DNA-binding transcription factors to guide the …

Epigenome plasticity in plants

JPB Lloyd, R Lister - Nature Reviews Genetics, 2022 - nature.com
Plant intra-individual and inter-individual variation can be determined by the epigenome, a
set of covalent modifications of DNA and chromatin that can alter genome structure and …

[HTML][HTML] Genome regulation by polycomb and trithorax: 70 years and counting

B Schuettengruber, HM Bourbon, L Di Croce, G Cavalli - Cell, 2017 - cell.com
Polycomb (PcG) and Trithorax (TrxG) group proteins are evolutionarily conserved chromatin-
modifying factors originally identified as part of an epigenetic cellular memory system that …

Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression

P Zhu, C Lister, C Dean - Nature, 2021 - nature.com
Plants use seasonal temperature cues to time the transition to reproduction. In Arabidopsis
thaliana, winter cold epigenetically silences the floral repressor locus FLOWERING LOCUS …

Glucose-driven TOR–FIE–PRC2 signalling controls plant development

R Ye, M Wang, H Du, S Chhajed, J Koh, K Liu, J Shin… - Nature, 2022 - nature.com
Nutrients and energy have emerged as central modulators of developmental programmes in
plants and animals,–. The evolutionarily conserved target of rapamycin (TOR) kinase is a …

Reconsidering plant memory: Intersections between stress recovery, RNA turnover, and epigenetics

PA Crisp, D Ganguly, SR Eichten, JO Borevitz… - Science …, 2016 - science.org
Plants grow in dynamic environments where they can be exposed to a multitude of stressful
factors, all of which affect their development, yield, and, ultimately, reproductive success …

The genetic basis of flowering responses to seasonal cues

F Andrés, G Coupland - Nature Reviews Genetics, 2012 - nature.com
Plants respond to the changing seasons to initiate developmental programmes precisely at
particular times of year. Flowering is the best characterized of these seasonal responses …

Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization

T Csorba, JI Questa, Q Sun… - Proceedings of the …, 2014 - National Acad Sciences
Long noncoding RNAs (lncRNAs) have been proposed to play important roles in gene
regulation. However, their importance in epigenetic silencing and how specificity is …

Vernalization-triggered intragenic chromatin loop formation by long noncoding RNAs

DH Kim, S Sung - Developmental cell, 2017 - cell.com
Long noncoding RNAs (lncRNAs) affect gene regulation through structural and regulatory
interactions with associated proteins. The Polycomb complex often binds to lncRNAs in …

The FLC Locus: A Platform for Discoveries in Epigenetics and Adaptation

C Whittaker, C Dean - Annual review of cell and developmental …, 2017 - annualreviews.org
Our understanding of the detailed molecular mechanisms underpinning adaptation is still
poor. One example for which mechanistic understanding of regulation has converged with …