Injury is a key driver of inflammation, a critical yet necessary response involving several
mediators that is aimed at restoring tissue homeostasis. Inflammation in the central nervous …

Objectives High prevalence of delirium superimposed on dementia (DSD) was previously
reported, with associated negative impact on hospitalized older adults. However, data were …

Background Delirium is an extremely common hospital complication. No study to date has
assessed whether a priori defined covariates; type of hospital setting and year of study …

Study objective To determine the effect of cognitive impairment (CI) and dementia on
adverse outcomes in older surgical patients. Design A systematic review and meta-analysis …

Objective The present work evaluates the relationship between postoperative immune and
neurovascular changes and the pathogenesis of surgery‐induced delirium superimposed …

Introduction Postoperative delirium (POD) is a common complication in elderly surgical
patients. Patients undergoing hip fractures surgery who are often characterized by advanced …

Background Frail kidney transplant (KT) recipients may be particularly vulnerable to surgical
stressors, resulting in delirium and subsequent adverse outcomes. We sought to identify the …

Study objective To assess the incidence of postoperative delirium and its outcomes in older
non-cardiac surgical patients. Design A systematic review and meta-analysis with multiple …

Delirium is a common postoperative complication in elderly hip fracture patients that
seriously affects patients' lives and health, and early delirium risk prediction, and targeted …

Background The objectives of this study were to delineate whether delirium in older adults is
associated with activation of the immune-inflammatory response system (IRS) as indicated …