The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …

Background and Aims Alcohol use disorder (AUD) is associated with microbial alterations
that worsen with cirrhosis. Fecal microbiota transplant (FMT) could be a promising approach …

Clostridioides difficile infection occurs when the bacterium produces toxin that causes
diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to …

Both genetic susceptibility and environmental factors are important contributors to
autoimmune disease pathogenesis. As an environmental factor, the gut microbiome plays a …

Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

Fecal microbiota transplantation (FMT) is recommended therapy for multiply recurrent
Clostridioides difficile infection. We report adverse events in 7 patients who received FMT …

Patients with chronic liver disease and cirrhosis demonstrate a global mucosal immune
impairment, which is associated with altered gut microbiota composition and functionality …

Human gut microbiota plays critical roles in physiology and disease. Our understanding of
ecological principles that govern the dynamics and resilience of this highly complex …

Intra-and interindividual variation in drug responses is one major reason for the failure of
drug therapy, drug toxicity, and even the death of patients. Precision medicine, or …