[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Surface functionalization of nanoparticles with polyethylene glycol: effects on protein adsorption and cellular uptake

B Pelaz, P del Pino, P Maffre, R Hartmann, M Gallego… - ACS …, 2015 - ACS Publications
Here we have investigated the effect of enshrouding polymer-coated nanoparticles (NPs)
with polyethylene glycol (PEG) on the adsorption of proteins and uptake by cultured cells …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Noninvasive photothermal cancer therapy nanoplatforms via integrating nanomaterials and functional polymers

Q Ban, T Bai, X Duan, J Kong - Biomaterials science, 2017 - pubs.rsc.org
In the cutting-edge field of cancer therapy, noninvasive photothermal therapy (PTT) has
received great attention because it is considered to overcome the drawbacks of …

Amphiphilic copolymers in biomedical applications: Synthesis routes and property control

F Perin, A Motta, D Maniglio - Materials Science and Engineering: C, 2021 - Elsevier
The request of new materials, matching strict requirements to be applied in precision and
patient-specific medicine, is pushing for the synthesis of more and more complex block …

Self-carried curcumin nanoparticles for in vitro and in vivo cancer therapy with real-time monitoring of drug release

J Zhang, S Li, FF An, J Liu, S Jin, JC Zhang, PC Wang… - Nanoscale, 2015 - pubs.rsc.org
The use of different nanocarriers for delivering hydrophobic pharmaceutical agents to tumor
sites has garnered major attention. Despite the merits of these nanocarriers, further studies …

Micellization of synthetic and polysaccharides-based graft copolymers in aqueous media

LI Atanase, J Desbrieres, G Riess - Progress in Polymer Science, 2017 - Elsevier
This review highlights recent advances in the micellization of synthetic graft copolymers and
those based on natural precursors, particularly polysaccharides. Synthesis and …

cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo

Y Zhu, J Zhang, F Meng, C Deng, R Cheng… - Journal of controlled …, 2016 - Elsevier
Biodegradable micelles are one of the most studied systems for the delivery of hydrophobic
anticancer drugs. Their therapeutic efficacy in vivo is, however, suboptimal, partly due to …