[HTML][HTML] Lipid-Centric Approaches in Combating Infectious Diseases: Antibacterials, Antifungals and Antivirals with Lipid-Associated Mechanisms of Action

OS Ostroumova, SS Efimova - Antibiotics, 2023 - mdpi.com
One of the global challenges of the 21st century is the increase in mortality from infectious
diseases against the backdrop of the spread of antibiotic-resistant pathogenic …

[HTML][HTML] Repurposing anti-cancer porphyrin derivative drugs to target SARS-CoV-2 envelope

DA Mendonça, I Cadima-Couto, CC Buga… - Biomedicine & …, 2024 - Elsevier
Antiviral medicines to treat COVID-19 are still scarce. Porphyrins and porphyrin derivatives
(PDs) usually present broad-spectrum antiviral activity with low risk of resistance …

Efficient and selective, in vitro and in vivo, antimicrobial photodynamic therapy with a dicationic chlorin in combination with KI

AS Amorim, ZA Arnaut, AI Mata, B Pucelik… - ACS Infectious …, 2024 - ACS Publications
Various cationic photosensitizers employed in antimicrobial photodynamic therapy (aPDT)
have the ability to photoinactivate planktonic bacteria under conditions of low phototoxicity to …

[HTML][HTML] Photodynamic inactivation of E. coli with cationic imidazolyl-porphyrin photosensitizers and their synergic combination with antimicrobial cinnamaldehyde

MFC Silva, RT Aroso, JM Dabrowski, B Pucelik… - Photochemical & …, 2024 - Springer
Bacterial infections are a global health concern, particularly due to the increasing resistance
of bacteria to antibiotics. Multi-drug resistance (MDR) is a considerable challenge, and novel …