Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
[HTML][HTML] Regulation of exosome production and cargo sorting
H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
Comprehensive landscape of extracellular vesicle-derived RNAs in cancer initiation, progression, metastasis and cancer immunology
W Hu, C Liu, ZY Bi, Q Zhou, H Zhang, LL Li, J Zhang… - Molecular cancer, 2020 - Springer
Extracellular vesicles (EVs), a class of heterogeneous membrane vesicles, are generally
divided into exosomes and microvesicles on basis of their origination from the endosomal …
divided into exosomes and microvesicles on basis of their origination from the endosomal …
Mechanism of cargo sorting into small extracellular vesicles
Y Chen, Y Zhao, Y Yin, X Jia, L Mao - Bioengineered, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are special membranous structures released by almost every
cell type that carry and protect some biomolecules from being degraded. They transport …
cell type that carry and protect some biomolecules from being degraded. They transport …
Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
Small extracellular vesicles: a novel avenue for cancer management
Y Gao, Y Qin, C Wan, Y Sun, J Meng, J Huang… - Frontiers in …, 2021 - frontiersin.org
Extracellular vesicles are small membrane particles derived from various cell types. EVs are
broadly classified as ectosomes or small extracellular vesicles, depending on their …
broadly classified as ectosomes or small extracellular vesicles, depending on their …
The role of extracellular vesicles in cancer: cargo, function, and therapeutic implications
J Jabalee, R Towle, C Garnis - Cells, 2018 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound structures
that play key roles in intercellular communication. EVs are potent regulators of …
that play key roles in intercellular communication. EVs are potent regulators of …
The roles of exosomes in cancer drug resistance and its therapeutic application
S Li, M Yi, B Dong, Y Jiao, S Luo… - Clinical and translational …, 2020 - Wiley Online Library
Exosomes are a category of extracellular vesicles with a size ranging from 40 to 160 nm,
which can be secreted by multiple cells in the tumor microenvironment. Exosomes serve as …
which can be secreted by multiple cells in the tumor microenvironment. Exosomes serve as …