GABAA receptor subtype involvement in addictive behaviour
DN Stephens, SL King, JJ Lambert… - Genes, Brain and …, 2017 - Wiley Online Library
GABAA receptors form the major class of inhibitory neurotransmitter receptors in the
mammalian brain. This review sets out to summarize the evidence that variations in genes …
mammalian brain. This review sets out to summarize the evidence that variations in genes …
Shared mechanisms of GABAergic and opioidergic transmission regulate corticolimbic reward systems and cognitive aspects of motivational behaviors
The functional interplay between the corticolimbic GABAergic and opioidergic systems plays
a crucial role in regulating the reward system and cognitive aspects of motivational …
a crucial role in regulating the reward system and cognitive aspects of motivational …
GABRB2, a key player in neuropsychiatric disorders and beyond
M Barki, H Xue - Gene, 2022 - Elsevier
The GABA receptors represent the main inhibitory system in the central nervous system that
ensure synaptogenesis, neurogenesis, and the regulation of neuronal plasticity and …
ensure synaptogenesis, neurogenesis, and the regulation of neuronal plasticity and …
Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron–astrocyte–microglia dysregulation
RK Yeung, ZH Xiang, SY Tsang, R Li, TYC Ho… - Translational …, 2018 - nature.com
Intronic polymorphisms of the GABAA receptor β2 subunit gene (GABRB2) under adaptive
evolution were associated with schizophrenia and reduced expression, especially of the …
evolution were associated with schizophrenia and reduced expression, especially of the …
Meta-analyses of genome wide association studies in lines of laying hens divergently selected for feather pecking using imputed sequence level genotypes
C Falker-Gieske, H Iffland, S Preuß, W Bessei… - BMC genetics, 2020 - Springer
Background Feather pecking (FP) is damaging behavior in laying hens leading to global
economic losses in the layer industry and massive impairments of animal welfare. The …
economic losses in the layer industry and massive impairments of animal welfare. The …
GABRB2 plays an important role in the lymph node metastasis of papillary thyroid cancer
Y Jin, W Jin, Z Zheng, E Chen, Q Wang, Y Wang… - Biochemical and …, 2017 - Elsevier
Background Thyroid cancer is a common malignant tumor of the endocrine system. Its
incidence has increased continuously worldwide for the past three decades. With advanced …
incidence has increased continuously worldwide for the past three decades. With advanced …
Highly Recurrent Copy Number Variations in GABRB2 Associated With Schizophrenia and Premenstrual Dysphoric Disorder
Objective Although single-nucleotide polymorphisms in GABRB2, the gene encoding for
GABAA receptors β2 subunit, have been associated with schizophrenia (SCZ), it is unknown …
GABAA receptors β2 subunit, have been associated with schizophrenia (SCZ), it is unknown …
Association between GABA receptor delta subunit gene polymorphisms and heroin addiction
X Xie, J Gu, D Zhuang, W Shen, L Li, Y Liu, W Xu… - Neuroscience …, 2021 - Elsevier
Evidence suggests that γ-aminobutyric acid (GABA) receptors are involved in the
development of drug dependence. Considering its exclusively extrasynaptic localization …
development of drug dependence. Considering its exclusively extrasynaptic localization …
Association Study of Genetic Polymorphisms in GABRD with Treatment Response and Dose in Methadone Maintenance Treatment
X Xie, J Gu, D Zhuang, X Chen, Y Zhou… - Personalized …, 2021 - Taylor & Francis
Aim: This study determined if gene variants in the GABA receptor delta subunit (GABRD) are
associated with treatment response and dose in methadone maintenance treatment (MMT) …
associated with treatment response and dose in methadone maintenance treatment (MMT) …
[HTML][HTML] Copy number variation profile-based genomic typing of premenstrual dysphoric disorder in Chinese
Premenstrual dysphoric disorder (PMDD) affects nearly 5% of women of reproductive age.
Symptomatic heterogeneity, together with largely unknown genetics, has greatly hindered its …
Symptomatic heterogeneity, together with largely unknown genetics, has greatly hindered its …