ABSTRACT The Gram-negative bacterium Vibrio cholerae is responsible for the severe
diarrheal pandemic disease cholera, representing a major global public health concern …

OmpU is a multimeric, cation selective outer membrane protein of Vibrio and related species
that non-covalently interact with peptidoglycan layer. Interaction of OmpU with human host …

Vibrio cholerae is a Gram-negative bacterium that persists in aquatic reservoirs and causes
the diarrheal disease cholera upon entry into a human host. V. cholerae employs the second …

ToxR, a Vibrio cholerae transmembrane one-component signal transduction factor, lies
within a regulatory cascade that results in the expression of ToxT, toxin coregulated pilus …

Vibrio parahaemolyticus, the leading causative agent of seafood-associated gastroenteritis,
harbors two major virulence gene loci T3SS1 and Vp-PAI (T3SS2 and tdh2). ToxR is a …

Outer membrane vesicles (OMVs) are continuously produced by Gram-negative bacteria
and are increasingly recognized as ubiquitous mediators of bacterial physiology. In …

Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis, harbors
two separate T6SSs on chromosomes 1 and 2, ie, T6SS1 (VP1386-1420) and T6SS2 …

Vibrio cholerae is an aquatic organism that causes the severe acute diarrheal disease
cholera. The ability of V. cholerae to cause disease is dependent upon the production of two …

The virulence regulator ToxR initiates and coordinates gene expression needed by Vibrio
cholerae to colonize the small intestine and cause disease. Despite its prominence in V …

Extracellular vesicles secreted by Gram-negative bacteria have proven to be important in
bacterial defense, communication and host–pathogen relationships. They resemble smaller …