Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease
DA Lane, PJ Grant - Blood, The Journal of the American Society …, 2000 - ashpublications.org
The development of thrombotic disorders in humans is one of the most common causes of
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …
Established and emerging cardiovascular risk factors
D Wood - American heart journal, 2001 - Elsevier
Background In the context of a comprehensive population strategy to reduce tobacco use,
encourage healthy food choices, and increase physical activity for the whole population, the …
encourage healthy food choices, and increase physical activity for the whole population, the …
Prevention of coronary heart disease in clinical practice. Summary of recommendations of the Second Joint Task Force of European and other Societies* on Coronary …
D Wood, G De Backer, O Faergeman… - Journal of …, 1998 - journals.lww.com
Since the first Joint European Societies (European Society of Cardiology, European
Atherosclerosis Society and European Society of Hypertension) Task Force …
Atherosclerosis Society and European Society of Hypertension) Task Force …
Interleukin-6 gene− 174g> c and− 572g> c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery
DJ Brull, HE Montgomery, J Sanders… - … , and vascular biology, 2001 - Am Heart Assoc
Interleukin-6 (IL-6) synthesized in response to diverse stimuli may play an important role in
bridging the inflammatory and atherosclerotic processes. The acute-phase response after …
bridging the inflammatory and atherosclerotic processes. The acute-phase response after …
Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review
SM Boekholdt, NR Bijsterveld, AHM Moons, M Levi… - Circulation, 2001 - Am Heart Assoc
Background—It is pathophysiologically conceivable that genetic variations in coagulation
and fibrinolytic proteins are associated with the risk of myocardial infarction. Methods and …
and fibrinolytic proteins are associated with the risk of myocardial infarction. Methods and …
Association of the Platelet Glycoprotein Ia C807T Gene Polymorphism With Nonfatal Myocardial Infarction in Younger Patients
S Santoso, TJ Kunicki, H Kroll… - Blood, The Journal …, 1999 - ashpublications.org
Recently, we have shown that two alleles of the glycoprotein (GP) Ia gene, designated C807
and T807, are associated with low or high platelet GPIa-IIa density and consequently with …
and T807, are associated with low or high platelet GPIa-IIa density and consequently with …
Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'
B Keavney, J Danesh, S Parish… - International journal …, 2006 - academic.oup.com
Background Blood concentrations of fibrinogen have been associated with coronary heart
disease risk in epidemiological studies, but it is uncertain whether this association is causal …
disease risk in epidemiological studies, but it is uncertain whether this association is causal …
Fibrinogen-marker or mediator of vascular disease?
WH Reinhart - Vascular Medicine, 2003 - journals.sagepub.com
Fibrinogen plays a key role in platelet aggregation, the final step of the coagulation cascade,
ie the formation of fibrin, and it is a major determinant of plasma viscosity and erythrocyte …
ie the formation of fibrin, and it is a major determinant of plasma viscosity and erythrocyte …
Hemostatic risk factors and arterial thrombotic disease
AP Reiner, DS Siscovick… - Thrombosis and …, 2001 - thieme-connect.com
The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental
factors related to atherosclerosis and thrombosis. Acute thrombosis at the site of a ruptured …
factors related to atherosclerosis and thrombosis. Acute thrombosis at the site of a ruptured …
Polymorphisms in coagulation factor genes and their impact on arterial and venous thrombosis
G Endler, C Mannhalter - Clinica chimica acta, 2003 - Elsevier
Arterial and venous thromboses, with their clinical manifestations such as stroke, myocardial
infarction (MI), or pulmonary embolism, are the major causes of death in developed …
infarction (MI), or pulmonary embolism, are the major causes of death in developed …