Purging and accumulation of genetic load in conservation
Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …
has been greatly improved by advances in genome sequencing and computational …
Evolutionary constraint and innovation across hundreds of placental mammals
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
Extinction risk of the world's freshwater mammals
E Sanders, S Wassens, DR Michael… - Conservation …, 2024 - Wiley Online Library
The continued loss of freshwater habitats poses a significant threat to global biodiversity. We
reviewed the extinction risk of 166 freshwater aquatic and semiaquatic mammals—a group …
reviewed the extinction risk of 166 freshwater aquatic and semiaquatic mammals—a group …
Functional genomic diversity is correlated with neutral genomic diversity in populations of an endangered rattlesnake
Theory predicts that genetic erosion in small, isolated populations of endangered species
can be assessed using estimates of neutral genetic variation, yet this widely used approach …
can be assessed using estimates of neutral genetic variation, yet this widely used approach …
Unifying approaches from statistical genetics and phylogenetics for mapping phenotypes in structured populations
In both statistical genetics and phylogenetics, a major goal is to identify correlations between
genetic loci or other aspects of the phenotype or environment and a focal trait. In these 2 …
genetic loci or other aspects of the phenotype or environment and a focal trait. In these 2 …
Mind the lag: understanding genetic extinction debt for conservation
The delay between disturbance events and genetic responses within populations is a
common but surprisingly overlooked phenomenon in ecology and evolutionary and …
common but surprisingly overlooked phenomenon in ecology and evolutionary and …
Genomic analyses capture the human-induced demographic collapse and recovery in a wide-ranging cervid
C Kessler, ABA Shafer - Molecular Biology and Evolution, 2024 - academic.oup.com
The glacial cycles of the Quaternary heavily impacted species through successions of
population contractions and expansions. Similarly, populations have been intensely shaped …
population contractions and expansions. Similarly, populations have been intensely shaped …
Whole genomes inform genetic rescue strategy for montane red foxes in North America
CB Quinn, S Preckler-Quisquater… - Molecular Biology …, 2024 - academic.oup.com
A few iconic examples have proven the value of facilitated gene flow for counteracting
inbreeding depression and staving off extinction; yet, the practice is often not implemented …
inbreeding depression and staving off extinction; yet, the practice is often not implemented …
Extensive Phylogenomic Discordance and the Complex Evolutionary History of the Neotropical Cat Genus Leopardus
J Lescroart, A Bonilla-Sánchez… - Molecular Biology …, 2023 - academic.oup.com
Even in the genomics era, the phylogeny of Neotropical small felids comprised in the genus
Leopardus remains contentious. We used whole-genome resequencing data to construct a …
Leopardus remains contentious. We used whole-genome resequencing data to construct a …
AI-informed conservation genomics
C van Oosterhout - Heredity, 2024 - nature.com
Genomic data and Artificial Intelligence (AI) models will start to play an increasingly
important role in conservation biology. In a recent study, Wilder et al.(2023) analysed …
important role in conservation biology. In a recent study, Wilder et al.(2023) analysed …