Purging and accumulation of genetic load in conservation

N Dussex, HE Morales, C Grossen, L Dalén… - Trends in ecology & …, 2023 - cell.com
Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …

Evolutionary constraint and innovation across hundreds of placental mammals

MJ Christmas, IM Kaplow, DP Genereux, MX Dong… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

Extinction risk of the world's freshwater mammals

E Sanders, S Wassens, DR Michael… - Conservation …, 2024 - Wiley Online Library
The continued loss of freshwater habitats poses a significant threat to global biodiversity. We
reviewed the extinction risk of 166 freshwater aquatic and semiaquatic mammals—a group …

Functional genomic diversity is correlated with neutral genomic diversity in populations of an endangered rattlesnake

S Mathur, AJ Mason, GS Bradburd… - Proceedings of the …, 2023 - National Acad Sciences
Theory predicts that genetic erosion in small, isolated populations of endangered species
can be assessed using estimates of neutral genetic variation, yet this widely used approach …

Unifying approaches from statistical genetics and phylogenetics for mapping phenotypes in structured populations

JG Schraiber, MD Edge, M Pennell - PLoS biology, 2024 - journals.plos.org
In both statistical genetics and phylogenetics, a major goal is to identify correlations between
genetic loci or other aspects of the phenotype or environment and a focal trait. In these 2 …

Mind the lag: understanding genetic extinction debt for conservation

R Gargiulo, KB Budde, M Heuertz - Trends in Ecology & Evolution, 2024 - cell.com
The delay between disturbance events and genetic responses within populations is a
common but surprisingly overlooked phenomenon in ecology and evolutionary and …

Genomic analyses capture the human-induced demographic collapse and recovery in a wide-ranging cervid

C Kessler, ABA Shafer - Molecular Biology and Evolution, 2024 - academic.oup.com
The glacial cycles of the Quaternary heavily impacted species through successions of
population contractions and expansions. Similarly, populations have been intensely shaped …

Whole genomes inform genetic rescue strategy for montane red foxes in North America

CB Quinn, S Preckler-Quisquater… - Molecular Biology …, 2024 - academic.oup.com
A few iconic examples have proven the value of facilitated gene flow for counteracting
inbreeding depression and staving off extinction; yet, the practice is often not implemented …

Extensive Phylogenomic Discordance and the Complex Evolutionary History of the Neotropical Cat Genus Leopardus

J Lescroart, A Bonilla-Sánchez… - Molecular Biology …, 2023 - academic.oup.com
Even in the genomics era, the phylogeny of Neotropical small felids comprised in the genus
Leopardus remains contentious. We used whole-genome resequencing data to construct a …

AI-informed conservation genomics

C van Oosterhout - Heredity, 2024 - nature.com
Genomic data and Artificial Intelligence (AI) models will start to play an increasingly
important role in conservation biology. In a recent study, Wilder et al.(2023) analysed …