Lung macrophages play important roles in the maintenance of homeostasis, pathogen
clearance and immune regulation. The different types of pulmonary macrophages and their …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …

As the first line of defence in the lung, alveolar macrophage contributes to maintaining lung
immune homoeostasis. Characterized by the heterogeneity and plasticity, macrophages …

Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …

Macrophages residing in various tissue types are unique in terms of their anatomical
locations, ontogenies, developmental pathways, gene expression patterns, and …

Alveolar macrophages (AMs) reside on the luminal surface of the airways and alveoli,
ensuring proper gas exchange by ingesting cellular debris and pathogens, and regulating …

Chronic obstructive pulmonary disease (COPD) patients frequently suffer from multiple
comorbidities, resulting in poor outcomes for these patients. Diabetes is observed at a …

Rationale: Interstitial macrophages (IMs) and airspace macrophages (AMs) play critical roles
in lung homeostasis and host defense, and are central to the pathogenesis of a number of …

Rationale: Chronic obstructive pulmonary disease (COPD) is a disease characterized by
persistent airway inflammation and disordered macrophage function. The extent to which …

In the face of ineffective vaccines, increasing antibiotic resistance and the decline in new
antibacterial drugs in the pipeline, tuberculosis (TB) still remains pandemic. Exposure to …