[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications

T Bauleth-Ramos, N El-Sayed, F Fontana, M Lobita… - Materials Today, 2023 - Elsevier
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024 - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

M Sang, M Cho, S Lim, IS Min, Y Han, C Lee, J Shin… - Science …, 2023 - science.org
Continuous glucose monitoring (CGM) allows patients with diabetes to manage critical
disease effectively and autonomously and prevent exacerbation. A painless, wireless …

Built‐in active microneedle patch with enhanced autonomous drug delivery

MA Lopez‐Ramirez, F Soto, C Wang… - Advanced …, 2020 - Wiley Online Library
The use of microneedles has facilitated the painless localized delivery of drugs across the
skin. However, their efficacy has been limited by slow diffusion of molecules and often …

Dissolvable Self‐Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy

SH Joo, J Kim, J Hong, S Fakhraei Lahiji… - Advanced …, 2023 - Wiley Online Library
Advancements in micro‐resolution 3D printers have significantly facilitated the development
of highly complex mass‐producible drug delivery platforms. Conventionally, due to the …

[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

Biodegradable microneedles fabricated with carbohydrates and proteins: Revolutionary approach for transdermal drug delivery

N Dabholkar, S Gorantla, T Waghule, VK Rapalli… - International Journal of …, 2021 - Elsevier
There has been a surge in the use of transdermal drug delivery systems (TDDS) for the past
few years. The market of TDDS is expected to reach USD 7.1 billion by 2023, from USD 5.7 …

[HTML][HTML] Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Marine polymeric microneedles for transdermal drug delivery

T Moniz, SAC Lima, S Reis - Carbohydrate Polymers, 2021 - Elsevier
Transdermal drug delivery is considered one of the most attractive routes for administration
of pharmaceutic and cosmetic active ingredients due to the numerous advantages …

Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process

O Howells, GJ Blayney, B Gualeni, JC Birchall… - European Journal of …, 2022 - Elsevier
The fabrication of silicon in-plane microneedle arrays from a simple single wet etch step is
presented. The characteristic 54.7° sidewall etch angle obtained via KOH etching of (1 0 0) …