The promises and the challenges of biotransformations in microflow

P Žnidaršič‐Plazl - Biotechnology journal, 2019 - Wiley Online Library
The challenges of transition toward the postpetroleum world shed light on the biocatalysis as
the most sustainable way for the valorization of biobased raw materials. However, its …

Supercritical CO2 applications in microfluidic systems

A Kazan - Microfluidics and Nanofluidics, 2022 - Springer
Supercritical fluid technology has been used for a variety of applications for decades and
received special attention in the fields of analytics, extraction and purification of valuable …

Biodegradation of crystalline cellulose nanofibers by means of enzyme immobilized-alginate beads and microparticles

A Kamdem Tamo, I Doench, A Morales Helguera… - Polymers, 2020 - mdpi.com
Recent advances in nanocellulose technology have revealed the potential of crystalline
cellulose nanofibers to reinforce materials which are useful for tissue engineering, among …

An enzyme immobilized microreactor for continuous‐flow biocatalysis of ginsenoside Rb1

A Kazan, X Hu, A Stahl, H Frerichs… - Journal of Chemical …, 2021 - Wiley Online Library
BACKGROUND Ginsenoside Rb1 is one of the major bioactive components of Panax
ginseng CA Meyer (Araliaceae), a medicinal plant that has been used for therapeutic …

Synthesis of alginate‐silica hybrid hydrogel for biocatalytic conversion by β‐glucosidase in microreactor

R Onbas, O Yesil‐Celiktas - Engineering in Life Sciences, 2019 - Wiley Online Library
The organic–inorganic hybrid materials have been used in different fields to immobilize
biomolecules since they offer many advantages. The aim of this study was to optimize and …

Jet cutter technique as a tool to achieve high lipase hydrolytic activity

FLC Almeida, MP Silveira, ID Alvim, TB da Costa… - Food and Bioproducts …, 2023 - Elsevier
Lipase immobilization has been widely studied because it allows for enzyme reuse and
provides more assertive control over the catalytic process. This study aimed to evaluate the …

Application of β-glucuronidase-immobilised silica gel formulation to microfluidic platform for biotransformation of β-glucuronides

C Muderrisoglu, S Sargin, O Yesil-Celiktas - Biotechnology letters, 2018 - Springer
Objective To improve the efficiency of reactions of β-glucuronidase (GUS)-assisted
glucuronic acid (GluA) removal within a microfluidic system. Results β-glucuronidase from …

Modelling coupled dynamics of diffusive–convective mass transfer in a microfluidic device and determination of hydrodynamic dispersion coefficient

E Yildiz-Ozturk, M Yucel, C Muderrisoglu… - Journal of the Taiwan …, 2017 - Elsevier
One of the challenges in mathematical modelling of microchips is the lack of available data
for dispersion coefficients of biomolecules. The main focus of this study was to determine the …

Sequential co-immobilization of β-glucosidase and yeast cells on single polymer support for bioethanol production

B He, X Zhu, C Zhao, Y Ma, W Yang - Science China Chemistry, 2018 - Springer
Co-immobilization of enzymes and microorganism is an effective way to enable cells to use
nonmetabolizable substrates and accelerate reaction rate of overall process. Herein, a facile …

A Study of Chemoenzymatic and Multi-Enzymatic Microreactor Cascades for the Synthesis of Pharmaceutical Compounds in Continuous Flow

M Santos - 2023 - search.proquest.com
Biocatalytic cascades have emerged as efficient tools in the synthesis of valuable
pharmaceutical compounds. Multi-enzymatic and chemoenzymatic cascades offer several …