Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future

G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …

[PDF][PDF] Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs

M Asai, Y Li, SM Newton, BD Robertson… - FEMS Microbiology …, 2023 - academic.oup.com
Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

The greater wax moth Galleria mellonella: biology and use in immune studies

I Wojda, B Staniec, M Sułek… - Pathogens and …, 2020 - academic.oup.com
The greater wax moth Galleria mellonella is an invertebrate that is increasingly being used
in scientific research. Its ease of reproduction, numerous offspring, short development cycle …

The Virtuous Galleria mellonella Model for Scientific Experimentation

I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Microbiology's next top model: Galleria in the molecular age

H Dinh, L Semenec, SS Kumar, FL Short… - Pathogens and …, 2021 - academic.oup.com
Galleria mellonella has risen to fame as an invertebrate model organism given its ethical
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …

UtilisingGalleria mellonella larvae for studying in vivo activity of conventional and novel antimicrobial agents

M Piatek, G Sheehan, K Kavanagh - Pathogens and Disease, 2020 - academic.oup.com
The immune response of insects displays many structural and functional similarities to the
innate immune response of mammals. As a result of these conserved features, insects may …

Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv

M Asai, Y Li, J Spiropoulos, W Cooley, DJ Everest… - Virulence, 2022 - Taylor & Francis
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a leading cause of
infectious disease mortality. Animal infection models have contributed substantially to our …

A Klebsiella pneumoniae DedA family membrane protein is required for colistin resistance and for virulence in wax moth larvae

V Tiwari, PR Panta, CE Billiot, MV Douglass… - Scientific reports, 2021 - nature.com
Ineffectiveness of carbapenems against multidrug resistant pathogens led to the increased
use of colistin (polymyxin E) as a last resort antibiotic. A gene belonging to the DedA family …

Innate Immune Responses of Galleria mellonella to Mycobacterium bovis BCG Challenge Identified Using Proteomic and Molecular Approaches

M Asai, G Sheehan, Y Li, BD Robertson… - Frontiers in cellular …, 2021 - frontiersin.org
The larvae of the insect Galleria mellonella, have recently been established as a non-
mammalian infection model for the Mycobacterium tuberculosis complex (MTBC). To gain …

[HTML][HTML] Impact of diesel exhaust particles on infections with Mycobacterium bovis BCG in in vitro human macrophages and an in vivo Galleria mellonella model

P Rodríguez-Fernández, I Romero-Andrada… - Environmental …, 2024 - Elsevier
There are strong suggestions for a link between pulmonary tuberculosis (TB) and air quality.
Diesel exhaust is one of the main contributors to pollution and it is reported to be able to …