Angiogenesis is a multistep process driven by a wide range of positive and negative
regulatory factors. Extracellular matrix (ECM) plays a crucial role in the regulation of this …

Studying the complex mechanisms of tumorigenesis and examining the interactions of
neoplastic cells within tumor ecosystem are critical to explore the possibility of effective …

Introduction: The 37/67 kDa high-affinity laminin receptor (laminin receptor precursor/laminin
receptor, LRP/LR) is a multi-faceted cellular receptor. It plays a vital role in the malignancy of …

The non-integrin laminin receptor, here designated the 37-kDa/67-kDa laminin receptor
(LRP/LR), is involved in many physiologically relevant processes, as well as numerous …

Introduction: The ubiquitously expressed 37 kDa/67 kDa high-affinity laminin receptor
(laminin receptor precursor/laminin receptor, LRP/LR) is a protein found to play several roles …

Cancer is a global burden due to high incidence and mortality rates and is ranked the
second most diagnosed disease amongst non-communicable diseases in South Africa. A …

Neuronal loss is a major neuropathological hallmark of Alzheimer's disease (AD). The
associations between soluble Aβ oligomers and cellular components cause this …

Adhesion and invasion have been identified as the two key components of metastasis. The
37 kDa/67 kDa laminin receptor (LRP/LR) is thought to enhance these two processes thus …

Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin
and cancer cell invasion - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

The neuronal perturbations in Alzheimer's disease are attributed to the formation of
extracellular amyloid-β (Aβ) neuritic plaques, composed predominantly of the neurotoxic Aβ …