Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

Melatonin is a signal molecule that modulates the biological circadian rhythms of
vertebrates. Melatonin deficiency is thought to be associated with several disorders …

Excessive iron has emerged in a large population of patients suffering from degenerative or
hematological diseases with a common outcome, osteoporosis. However, its underlying …

Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Methyltransferase-like 3 (METTL3) is the main enzyme for N 6-methyladenosine (m 6 A)-
based methylation of RNAs and it has been implicated in many biological and …

Bone marrow-derived mesenchymal stem cells (BMSCs) have been suggested to possess
the capacity to differentiate into different cell lineages. Maintaining a balanced stem cell …

Excess iron has been reported to lead to osteoblastic cell damage, which is a crucial
pathogenesis of iron overload‐related osteoporosis. However, the cytotoxic mechanisms …

Stem cell senescence is an important cause of aging. Delaying senescence may present a
novel way to combat aging and age‐associated diseases. This study provided a mechanistic …

Osteoporosis is a systemic metabolic disease, mainly characterized by reduced bone
mineral density and destruction of bone tissue microstructure. However, the molecular …

Autophagy is an evolutionarily conserved intracellular process and is considered one of the
main catabolism pathways. In the process of autophagy, cells are digested nonselectively or …