Innovations in the insect cell expression system for industrial recombinant vaccine antigen production

MMJ Cox - Vaccines, 2021 - mdpi.com
The insect cell expression system has previously been proposed as the preferred
biosecurity strategy for production of any vaccine, particularly for future influenza pandemic …

The magic staff: a comprehensive overview of baculovirus-based technologies applied to human and animal health

ML Pidre, PN Arrías, LC Amorós Morales… - Viruses, 2022 - mdpi.com
Baculoviruses are enveloped, insect-specific viruses with large double-stranded DNA
genomes. Among all the baculovirus species, Autographa californica multiple …

Solutions against emerging infectious and noninfectious human diseases through the application of baculovirus technologies

AM Targovnik, JA Simonin, GJ Mc Callum… - Applied microbiology …, 2021 - Springer
Baculoviruses are insect pathogens widely used as biotechnological tools in different fields
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …

Baculoviruses in gene therapy and personalized medicine

S Schaly, M Ghebretatios, S Prakash - Biologics: Targets and …, 2021 - Taylor & Francis
This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …

Production of rabies VLPs in insect cells by two monocistronic baculoviruses approach

TC Bernardino, RM Astray, CA Pereira… - Molecular …, 2021 - Springer
Rabies is an ancient zoonotic disease that still causes the death of over 59,000 people
worldwide each year. The rabies lyssavirus encodes five proteins, including the envelope …

[HTML][HTML] Clinical and Translational Landscape of Viral Gene Therapies

A Yudaeva, A Kostyusheva, A Kachanov, S Brezgin… - Cells, 2024 - mdpi.com
Gene therapies hold significant promise for treating previously incurable diseases. A
number of gene therapies have already been approved for clinical use. Currently, gene …

Recent strategies to achieve high production yield of recombinant protein: A review

CZ Tepap, J Anissi, S Bounou - Journal of Cellular …, 2023 - content.iospress.com
Recombinant proteins have long been used in the pharmaceutical, chemical, and
agricultural industries. These proteins can be produced in hosts such as mammalian cells …

The Development of Epitope-Based Recombinant Protein Vaccines against SARS-CoV-2

K Khalid, HX Lim, JS Hwang, CL Poh - The AAPS Journal, 2024 - Springer
The COVID-19 pandemic continues to cause infections and deaths, which are attributable to
the SARS-CoV-2 Omicron variant of concern (VOC). Moderna's response to the declining …

[HTML][HTML] Prophylactic ribonucleic acid vaccines to combat rna viral infections in humans

IVS Louis, J Abadie - RNA Therapeutics-History, Design …, 2022 - intechopen.com
Vaccines have evolved as widely applicable and available prophylaxes against infectious
diseases. Advances in ribonucleic acid technologies revolutionized the biopharmaceutical …

Production Technologies for Recombinant Antibodies: Insights into Eukaryotic, Prokaryotic, and Transgenic Expression Systems

MZ Saleem, GZ Jahangir, A Saleem, A Zulfiqar… - Biochemical …, 2024 - Springer
Recombinant antibodies, a prominent class of recombinant proteins, are witnessing
substantial growth in research and diagnostics. Recombinant antibodies are being …