[HTML][HTML] Rational consideration of Akkermansia muciniphila targeting intestinal health: advantages and challenges

Y Luo, C Lan, H Li, Q Ouyang, F Kong, A Wu… - npj Biofilms and …, 2022 - nature.com
As one of the promising next-generation probiotics (NGPs), Akkermansia muciniphila, a well-
known mucin-degrading bacterium, has been proven to be closely related to the metabolic …

[HTML][HTML] Microbiota-host-irinotecan axis: a new insight toward irinotecan chemotherapy

B Yue, R Gao, Z Wang, W Dou - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Irinotecan (CPT11) and its active metabolite ethyl-10-hydroxy-camptothecin (SN38) are
broad-spectrum cytotoxic anticancer agents. Both cause cell death in rapidly dividing cells …

[HTML][HTML] Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin… - Cancer cell, 2022 - cell.com
Microbial dysbiosis is a colorectal cancer (CRC) hallmark and contributes to inflammation,
tumor growth, and therapy response. Gut microbes signal via metabolites, but how the …

[HTML][HTML] Mucosal biofilms are an endoscopic feature of irritable bowel syndrome and ulcerative colitis

M Baumgartner, M Lang, H Holley, D Crepaz… - Gastroenterology, 2021 - Elsevier
Background & Aims Irritable bowel syndrome (IBS) and inflammatory bowel diseases result
in a substantial reduction in quality of life and a considerable socioeconomic impact. In IBS …

[HTML][HTML] Xiao-Chai-Hu-Tang ameliorates tumor growth in cancer comorbid depressive symptoms via modulating gut microbiota-mediated TLR4/MyD88/NF-κB …

S Shao, R Jia, L Zhao, Y Zhang, Y Guan, H Wen, J Liu… - Phytomedicine, 2021 - Elsevier
Background Depressive symptoms are thought to promote cancer development and
depressive remission has been reported to be effective for defeating cancer. The herbal …

[HTML][HTML] The relationship between gut microbiota and inflammatory response, learning and memory in mice by sleep deprivation

M Zhang, M Zhang, G Kou, Y Li - Frontiers in cellular and infection …, 2023 - frontiersin.org
Objective Sleep deprivation has developed into a common phenomenon, which can lead to
inflammatory responses and cognitive impairment, but the underlying mechanism is …

[HTML][HTML] Stachyose modulates gut microbiota and alleviates DSS-induced ulcerative colitis in mice

C Wang, J Bai, B Wang, L Yu, F Tian, J Zhao… - Food Science and …, 2023 - Elsevier
Stachyose is a prebiotic that traditionally extracted from plants, such as vegetable. It has
been demonstrated to alleviate intestinal inflammation by regulating gut microbiota, but the …

Potential role of Lactobacillus plantarum in colitis induced by dextran sulfate sodium through altering gut microbiota and host metabolism in murine model

S Ding, W Yan, J Fang, H Jiang, G Liu - Science China Life Sciences, 2021 - Springer
Inflammatory bowel disease (IBD) is a chronic lifelong disease characterized by
inflammation of the gastrointestinal tract. Although more and more treatment options serve …

Chemotherapeutic drugs induce different gut microbiota disorder pattern and NOD/RIP2/NF-κB signaling pathway activation that lead to different degrees of intestinal …

B Huang, M Gui, Z Ni, Y He, J Zhao, J Peng… - Microbiology …, 2022 - Am Soc Microbiol
Fluorouracil (5-FU), irinotecan (CPT-11), oxaliplatin (L-OHP), and calcium folinate (CF) are
widely used chemotherapeutic drugs to treat colorectal cancer. However, chemotherapeutic …

[HTML][HTML] Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis

F Yu, X Hu, HL Ren, X Wang, R Shi, J Guo… - Journal of Translational …, 2024 - Springer
Background Ulcerative colitisis (UC) classified as a form of inflammatory bowel diseases
(IBD) characterized by chronic, nonspecific, and recurrent symptoms with a poor prognosis …