Ceramides are a heterogeneous group of bioactive membrane sphingolipids that play
specialized regulatory roles in cellular metabolism depending on their characteristic fatty …

Childhood obesity is a major public health problem worldwide, and the relationship between
obesity and central precocious puberty has long been confirmed, however, the mechanisms …

This chapter discusses the modulatory influences regulating the timing of puberty in rats.
The developmental process that leads to puberty in the female rat is based on an …

Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked
to higher disease burden later in life. The mechanisms underlying this association remain …

▪ Abstract The raphe magnus is part of an interrelated region of medullary raphe and
ventromedial reticular nuclei that project to all areas of the spinal gray. Activation of raphe …

Circadian rhythms are generated by an endogenously organized timing system that drives
daily rhythms in behavior, physiology and metabolism. In mammals, the suprachiasmatic …

In order for any organism to function properly, it is crucial that it be table to control the timing
of its biological functions. An internal biological clock, located, in mammals, in the …

We studied the effects of a chronic intermittent cold stress regime on sympathetic nerve
activation and ovarian physiology. This paradigm (4° C for 3 h/day, Monday–Friday, for 3 or …

This article presents a review of the role of the sympathetic activity in ovarian pathologies
affecting reproductive function. We provide a succinct outline of the findings of our group in …

The lack of significant progress in the treatment of epithelial ovarian cancer (EOC)
underscores the need to gain a better understanding of the processes that lead to …