The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol
Most of the mitochondrial proteome originates from nuclear genes and is transported into the
mitochondria after synthesis in the cytosol. Complex machineries which maintain the …
mitochondria after synthesis in the cytosol. Complex machineries which maintain the …
ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER
Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid
metabolism and form tight structural associations, which were first observed in ultrastructural …
metabolism and form tight structural associations, which were first observed in ultrastructural …
Nanobody technology: a versatile toolkit for microscopic imaging, protein–protein interaction analysis, and protein function exploration
E Beghein, J Gettemans - Frontiers in immunology, 2017 - frontiersin.org
Over the last two decades, nanobodies or single-domain antibodies have found their way in
research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid …
research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid …
Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism [S]
PP Van Veldhoven - Journal of lipid research, 2010 - ASBMB
In humans, peroxisomes harbor a complex set of enzymes acting on various lipophilic
carboxylic acids, organized in two basic pathways, α-oxidation and β-oxidation; the latter …
carboxylic acids, organized in two basic pathways, α-oxidation and β-oxidation; the latter …
Metabolic functions of peroxisomes in health and disease
RJA Wanders - Biochimie, 2014 - Elsevier
Peroxisomes are subcellular organelles which are present in virtually every eukaryotic cell
and catalyze a large number of metabolic functions. The importance of peroxisomes for …
and catalyze a large number of metabolic functions. The importance of peroxisomes for …
Peroxisome-mitochondria interplay and disease
Peroxisomes and mitochondria are ubiquitous, highly dynamic organelles with an oxidative
type of metabolism in eukaryotic cells. Over the years, substantial evidence has been …
type of metabolism in eukaryotic cells. Over the years, substantial evidence has been …
Quantitation in mass-spectrometry-based proteomics
WX Schulze, B Usadel - Annual review of plant biology, 2010 - annualreviews.org
Mass-spectrometry-based proteomics, the large-scale analysis of proteins by mass
spectrometry, has emerged as a new technology over the last decade and become routine …
spectrometry, has emerged as a new technology over the last decade and become routine …
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism
Inherited disorders of vitamin B12 (cobalamin) have provided important clues to how this
vitamin, which is essential for hematological and neurological function, is transported and …
vitamin, which is essential for hematological and neurological function, is transported and …