Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Most of the mitochondrial proteome originates from nuclear genes and is transported into the
mitochondria after synthesis in the cytosol. Complex machineries which maintain the …

Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid
metabolism and form tight structural associations, which were first observed in ultrastructural …

Over the last two decades, nanobodies or single-domain antibodies have found their way in
research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid …

In humans, peroxisomes harbor a complex set of enzymes acting on various lipophilic
carboxylic acids, organized in two basic pathways, α-oxidation and β-oxidation; the latter …

Peroxisomes are subcellular organelles which are present in virtually every eukaryotic cell
and catalyze a large number of metabolic functions. The importance of peroxisomes for …

Peroxisomes and mitochondria are ubiquitous, highly dynamic organelles with an oxidative
type of metabolism in eukaryotic cells. Over the years, substantial evidence has been …

Mass-spectrometry-based proteomics, the large-scale analysis of proteins by mass
spectrometry, has emerged as a new technology over the last decade and become routine …

Inherited disorders of vitamin B12 (cobalamin) have provided important clues to how this
vitamin, which is essential for hematological and neurological function, is transported and …