[HTML][HTML] Flavonoids—Natural gifts to promote health and longevity

X Fan, Z Fan, Z Yang, T Huang, Y Tong… - International Journal of …, 2022 - mdpi.com
The aging of mammals is accompanied by the progressive atrophy of tissues and organs
and the accumulation of random damage to macromolecular DNA, protein, and lipids …

Paving Luteolin Therapeutic Potentialities and Agro‐Food‐Pharma Applications: Emphasis on In Vivo Pharmacological Effects and Bioavailability Traits

Y Taheri, J Sharifi-Rad, G Antika… - Oxidative Medicine …, 2021 - Wiley Online Library
Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As
many other natural flavonoids, it is often found in combination with glycosides in many fruits …

Role of reactive oxygen species in ultraviolet-induced photodamage of the skin

M Wei, X He, N Liu, H Deng - Cell division, 2024 - Springer
Reactive oxygen species (ROS), such as superoxides (O2•−) and hydroxyl groups (OH·), are
short-lived molecules containing unpaired electrons. Intracellular ROS are believed to be …

Redox activity of flavonoids: Impact on human health, therapeutics, and chemical safety

C Sarkar, P Chaudhary, S Jamaddar… - Chemical Research …, 2022 - ACS Publications
The cost-effectiveness of presently used therapies is a problem in overall redox-based
management, which is posing a significant financial burden on communities across the …

Mitochondrial dysfunction and DNA damage in the context of pathogenesis of atherosclerosis

T Shemiakova, E Ivanova, AV Grechko, EV Gerasimova… - Biomedicines, 2020 - mdpi.com
Atherosclerosis is a multifactorial disease of the cardiovascular system associated with
aging, inflammation, and oxidative stress. An important role in the development of …

Research Progress of Flavonoids Regulating Endothelial Function

H Li, Q Zhang - Pharmaceuticals, 2023 - mdpi.com
The endothelium, as the guardian of vascular homeostasis, is closely related to the
occurrence and development of cardiovascular diseases (CVDs). As an early marker of the …

Neuroprotective mechanisms of luteolin in glutamate-induced oxidative stress and autophagy-mediated neuronal cell death

W Vongthip, S Nilkhet, K Boonruang… - Scientific Reports, 2024 - nature.com
Neurodegenerative diseases, characterized by progressive neuronal dysfunction and loss,
pose significant health challenges. Glutamate accumulation contributes to neuronal cell …

Flavonoids as a therapeutical option for the treatment of thrombotic complications associated with COVID‐19

JP Quintal Martinez… - Phytotherapy …, 2023 - Wiley Online Library
The SARS‐CoV‐2 outbreak has been one of the largest public health crises globally, while
thrombotic complications have emerged as an important factor contributing to mortality …

Revisiting luteolin: An updated review on its anticancer potential

A Rauf, P Wilairatana, PB Joshi, Z Ahmad, A Olatunde… - Heliyon, 2024 - cell.com
Numerous natural products found in our diet, such as polyphenols and flavonoids, can
prevent the progression of cancer. Luteolin, a natural flavone, present in significant amounts …

Effects of Traditional Chinese Medication‐Based Bioactive Compounds on Cellular and Molecular Mechanisms of Oxidative Stress

B Liang, YC Zhu, J Lu, N Gu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
The oxidative stress reaction is the imbalance between oxidation and antioxidation in the
body, resulting in excessive production of oxygen free radicals in the body that cannot be …