Cellular membranes are formed from a chemically diverse set of lipids present in various
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …

Humans, like all mammals, partition their daily behaviour into activity (wakefulness) and rest
(sleep) phases that differ largely in their metabolic requirements. The circadian clock …

Intermittent fasting may impart metabolic benefits independent of energy balance by
initiating fasting-mediated mechanisms. This randomized controlled trial examined 24-hour …

Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of
exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal …

The epidemic of Type 2 diabetes mellitus necessitates development of novel therapeutic
and preventative strategies to attenuate expansion of this debilitating disease. Evidence …

Many molecular, physiological and behavioural processes display distinct 24-hour rhythms
that are directed by the circadian system. The master clock, located in the suprachiasmatic …

Lipids play important roles in energy metabolism along with diverse aspects of biological
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …

The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-
scale studies of the structure, composition, and quantity of lipids in biological systems such …

The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …

Methods In this three-armed parallel-group randomised trial undertaken at a university in
Melbourne, Australia, overweight/obese men consumed an HFD (65% of energy from fat) for …